Improved biological activity of a mutant endostatin containing a single amino-acid substitution [PDF]
, 2004 A Calvo +34 more
core +2 more sources
Regulation of cardiac responses to increased load : Role of endothelin-1, angiotensin II and collagen XV [PDF]
, 2002 Chronic overload of the heart is the major cause of left ventricular hypertrophy (LVH) and eventually heart failure. It is generally accepted that autocrine/paracrine factors, such as angiotensin II (Ang II) and endothelin-1 (ET-1) contribute to the ...
Piuhola, Jarkko
core
Type XVIII and XV collagens: primary structure of human alpha1(XVIII) chain, phenotypic studies of type XVIII collagen single null and type XVIII and XV collagen double null mice [PDF]
, 2003 In this thesis study, the primary structure of the human α1(XVIII) polypeptide was elucidated, its tissue distribution was studied, and the phenotypic changes in the mouse eye due to lack of type XVIII collagen in a knock-out mouse model were studied ...
Ylikärppä, Ritva
core
Endostatin Binds Tropomyosin [PDF]
Journal of Biological Chemistry, 2001 NicholasJ. MacDonald +9 more
openaire +1 more source
A real-world study of recombinant human endostatin combined with PD-1/PD-L1 blockade and chemotherapy for patients with advanced non-small cell lung cancer negative for actionable molecular biomarkers. [PDF]
Medicine (Baltimore), 2023 Zhao JW +6 more
europepmc +1 more source
Substrate specificity of lysyl hydroxylase isoforms and multifunctionality of lysyl hydroxylase 3 [PDF]
, 2008 Lysyl hydroxylase (LH) catalyzes the post-translational formation of hydroxylysines in collagens and collagenous proteins. Three lysyl hydroxylase isoforms, LH1, LH2 and LH3, have been identified from different species.
Risteli, Maija
core
The vascular development is modulated by endostatin and restin [PDF]
, 2003 Endostatin and restin are proteolytic fragments of collagen XVIII and XV. They are described in literature as anti-angiogenic and consequently tumour-inhibitory proteins.
Schmidt, Annette
core