Results 101 to 110 of about 444,778 (249)
Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, EarlyView.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Advanced Materials, EarlyView.Using a bottom‐up approach, we engineered a human neuromuscular microchip to investigate distinct adaptive responses to neural stimulation and metabolic stress. Further integration of endothelial cells revealed their critical role in modulating neuromuscular excitability, establishing a comprehensive neurovascular‐muscular model.
Jinchul Ahn +17 more
wiley +1 more source
Advanced Materials, EarlyView.This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris +11 more
wiley +1 more source
Fuchs endothelial corneal dystrophy: current perspectives
Clinical Ophthalmology, 2016 Gustavo Vedana, Guadalupe Villarreal Jr, Albert S Jun Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, MD, USA Abstract: Fuchs endothelial corneal dystrophy (FECD) is the most common corneal dystrophy and frequently results in ...
Vedana G, Villarreal Jr G, Jun AS
doaj
Nature CommunicationsBlood vessels undergo extensive remodelling to acquire appropriate diameters, yet how endothelial cells coordinate changes in their number and shape to achieve this remains unclear.
Yan Chen +14 more
doaj +1 more source
35 Review on endothelial cell loss of corneal transplants and possible correlations. [PDF]
BMJ Open Ophthalmol, 2022 Franz U +2 more
europepmc +1 more source
3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress
Advanced Materials Technologies, EarlyView.Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi +4 more
wiley +1 more source
A Cryopreservation‐Based Supply Chain Strategy for Extrusion Bioprinting in Space
Advanced Materials Technologies, EarlyView.Extrusion bioprinting on crewed space platforms requires a bioink that stays functional along the logistic chain. Here, cells and biomaterial ink travel separately, the cells cryopreserved and the ink cold stored, and are combined only minutes before printing.
Johannes Windisch +7 more
wiley +1 more source
Advanced Materials Technologies, EarlyView.A closed U‐shaped microfluidic platform symmetrically embeds a single, size‐controlled HT29 colorectal cancer spheroid within a GFP‐HUVEC‐laden fibrin matrix. HT29 spheroids are associated with hyper‐branched endothelial network remodeling, while vascularized co‐culture is accompanied by anisotropic protrusive growth and EMT‐like marker changes in the ...
G. Cretti +4 more
wiley +1 more source
A Superlubricated Magnetically Steerable Microcatheter with Integrated Optical and Fluidic Channels
Advanced Robotics Research, EarlyView.A magnetically steerable microcatheter with integrated optical and fluidic channels is developed for multifunctional navigation in tortuous anatomical environments. A surface‐grafted hydrogel coating enables low‐friction actuation. The device demonstrates stable light and fluid delivery during magnetic manipulation, offering a compact platform for ...
Yuntian Du +5 more
wiley +1 more source