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Role of Endothelial Cell–Cell Junctions in Endothelial Permeability

2011
The endothelial barrier separates the inner blood compartment from the surrounding tissues. At the molecular level, adhesion molecules accumulate at the endothelial cell-cell junction and contribute to maintain vascular integrity. An increase in the endothelial permeability is frequently associated with the deregulation of junctional adhesion. Here, we
Armelle Le Guelte, Julie Gavard
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Cells in focus: endothelial cell

The International Journal of Biochemistry & Cell Biology, 2002
The endothelial cell is thought to arise from the splanchnopleuric mesoderm. Endothelial cells form the inner lining of a blood vessel and provides an anticoagulant barrier between the vessel wall and blood. In addition to its role as a selective permeability barrier, the endothelial cell is a unique multifunctional cell with critical basal and ...
J Timothy Riley   +2 more
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Exercise and the endothelial cell

International Journal of Cardiology, 2005
Regular exercise is known to be effective in the prevention and treatment of cardiovascular disease. Among the cardioprotectant mechanisms influenced by exercise, the endothelium is becoming recognised as a major target. Preservation of endothelial cell structure is vital for frictionless blood flow, prevention of macrophage and lipid infiltration and,
Marsh, Susan A., Coombes, Jeff S.
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Endothelial Progenitor Cells

Annual Review of Medicine, 2005
Endothelial progenitor cells are a circulating, bone marrow–derived cell population that appears to participate in both vasculogenesis and vascular homeostasis. Questions persist regarding their functional characteristics, as well as the precise panel of cell surface markers that uniquely define this newly described progenitor cell population.
Aarif Y. Khakoo, Toren Finkel
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Endothelial cell functions

Journal of Cellular Physiology, 2003
AbstractEndothelial cells play a wide variety of critical roles in the control of vascular function. Indeed, since the early 1980s, the accumulating knowledge of the endothelial cell structure as well as of the functional properties of the endothelial cells shifted their role from a passive membrane or barrier to a complex tissue with complex functions
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Endothelial Precursor Cells

Stem Cell Reviews, 2007
The discovery and subsequent characterization of endothelial precursor cells (EPCs) has stimulated interest in their potential use in older persons. Understanding the mechanisms that underlie EPC availability and function has important clinical implications for this age group.
Daniel Eyman   +3 more
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The Proteome of Endothelial Cells

2006
Endothelial cells form a continuous monolayer lining the inside face of all blood vessels, and present the ability to selectively control vascular permeability. The endothelium is involved in a wide variety of normal physiological and pathological processes.
Jesús Egido   +5 more
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Endothelial Cells and Inflammation

Clinics in Laboratory Medicine, 1983
Recent studies have brought remarkable progress in the understanding of cellular, subcellular, and molecular mechanisms of endothelial injury and responses to injury, both of which appear to be integral parts of the acute inflammatory response. The possible roles of endothelial surface enzymes in the inflammatory response are explored.
James W. Ryan, Una S. Ryan
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Cell biology of endothelial cells

Human Pathology, 1987
Endothelial cells are a source of physiologically important molecules synthesized therein and secreted to the blood and/or to the subendothelial extracellular matrix. These molecules participate in formation of platelet and fibrin thrombi (e.g., von Willebrand factor and tissue factor) and contribute to antithrombotic properties of the endothelium (e.g.
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Endothelial cell tumors

Microscopy Research and Technique, 2003
AbstractHistorically, there has been much debate on the nature of infantile hemangiomas as either congenital malformations or benign neoplasms. Some vascular lesions that are present at birth and evidence no proliferative growth are considered to be congenital malformations; other post‐natal vascular tumors pursue aggressive and possibly lethal ...
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