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Endothelial stem and progenitor cells (stem cells): (2017 Grover Conference Series) [PDF]

open access: yesPulmonary Circulation, 2017
The capacity of existing blood vessels to give rise to new blood vessels via endothelial cell sprouting is called angiogenesis and is a well-studied biologic process.
Mervin C. Yoder
doaj   +4 more sources

Endothelial induced EMT in breast epithelial cells with stem cell properties. [PDF]

open access: yesPLoS ONE, 2011
Epithelial to mesenchymal transition (EMT) is a critical event in cancer progression and is closely linked to the breast epithelial cancer stem cell phenotype.
Valgardur Sigurdsson   +10 more
doaj   +3 more sources

Bone Morphogenetic Protein 9 Regulates Early Lymphatic-Specified Endothelial Cell Expansion during Mouse Embryonic Stem Cell Differentiation

open access: yesStem Cell Reports, 2019
Summary: Exogenous cues involved in the regulation of the initial steps of lymphatic endothelial development remain largely unknown. We have used an in vitro model based on the co-culture of vascular precursors derived from mouse embryonic stem cell (ESC)
Mariela Subileau   +6 more
doaj   +3 more sources

Comparative Analysis of Blood‐Derived Endothelial Cells for Designing Next‐Generation Personalized Organ‐on‐Chips

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Organ‐on‐chip technology has accelerated in vitro preclinical research of the vascular system, and a key strength of this platform is its promise to impact personalized medicine by providing a primary human cell–culture environment where ...
Tanmay Mathur   +2 more
doaj   +1 more source

Caspases and p38 MAPK regulate endothelial cell adhesiveness for mesenchymal stem cells. [PDF]

open access: yesPLoS ONE, 2013
Mesenchymal stem cells natively circulating or delivered into the blood stream home to sites of injury. The mechanism of mesenchymal stem cell homing to sites of injury is poorly understood.
Irina A Potapova   +2 more
doaj   +1 more source

Induction of Neurogenesis and Angiogenesis in a Rat Hemisection Spinal Cord Injury Model With Combined Neural Stem Cell, Endothelial Progenitor Cell, and Biomimetic Hydrogel Matrix Therapy

open access: yesCritical Care Explorations, 2021
OBJECTIVES:. Acute spinal cord injury is a devastating injury that may lead to loss of independent function. Stem-cell therapies have shown promise; however, a clinically efficacious stem-cell therapy has yet to be developed.
Eric J. Marrotte, DO, PhD   +6 more
doaj   +1 more source

Mesenchymal Stem Cells & Endothelial Function [PDF]

open access: yesEBioMedicine, 2015
In this issue of EBioMedicine, Premer et al. report their study titled “Allogeneic Mesenchymal Stem Cells Restore Endothelial Function in Heart Failure by Stimulating Endothelial Progenitor Cells” (Premer et al., 2015). They recruited a cohort of heart failure patients from two ongoing clinical trials evaluating both autologous and allogeneic ...
Kenneth M. Fish, Roger J. Hajjar
openaire   +3 more sources

Endothelial origin of mesenchymal stem cells [PDF]

open access: yesCell Cycle, 2011
Mesenchymal stem/stromal cells (MSCs) are fibroblastoid cells capable of long-term expansion and skeletogenic differentiation. While MSCs are known to originate from neural crest and mesoderm, immediate mesodermal precursors that give rise to MSCs have not been characterized.
Igor I, Slukvin, Maxim, Vodyanik
openaire   +2 more sources

Current concepts on endothelial stem cells definition, location, and markers

open access: yesStem Cells Translational Medicine, 2021
Ischemic vascular disease is a major cause of mortality and morbidity worldwide, and regeneration of blood vessels in perfusion‐deficient tissues is a worthwhile therapeutic goal. The idea of delivering endothelial stem/progenitor cells to repair damaged
Sarah E.J. Chambers   +8 more
doaj   +1 more source

Discovering the Potential of Dental Pulp Stem Cells for Corneal Endothelial Cell Production: A Proof of Concept

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Failure of corneal endothelium cell monolayer is the main cause leading to corneal transplantation. Autologous cell-based therapies are required to reconstruct in vitro the cell monolayer.
Begoña M. Bosch   +5 more
doaj   +1 more source

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