Results 201 to 210 of about 399,722 (264)

BCMA‐Engineered Dendritic Cell‐Derived Exosomes as Bi‐Functional Therapeutics Orchestrating Cytokine Sequestration and Immune Activation for Multiple Myeloma

Advanced Science, EarlyView.
A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng, Chao He, Zhibin He, Hongbo Chen, Fang Cheng, Yongjiang Zheng   +5 more
wiley   +1 more source

Correction to: Endothelial dysfunction in cardiovascular diseases: mechanisms and in vitro models. [PDF]

Mol Cell Biochem
Grego A, Fernandes C, Fonseca I, Dias-Neto M, Costa R, Leite-Moreira A, Oliveira SM, Trindade F, Nogueira-Ferreira R.   +8 more
europepmc   +1 more source

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

Advanced Science, EarlyView.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li, Zhonglian Cao, Rongrui Zhou, Xu Cheng, Xiaozhi Hu, Shuwen Xu, Zihan Dou, Ling Du, Dianwen Ju   +8 more
wiley   +1 more source

Inflammatory and Endothelial Dysfunction Biomarkers Predict Severe COVID-19 in Hospitalized Patients: Development of the CCBR Model. [PDF]

Biomedicines
Ciobanu S, Adamescu AI, Tilișcan C, Radu AM, Popescu B, Văcărașu AB, Marinescu AG, Aramă V, Aramă ȘS.   +8 more
europepmc   +1 more source

Activated platelets promote endothelial dysfunction and monocyte recruitment in early renal microvascular injury. [PDF]

J Inflamm (Lond)
Rustiasari UJ, Uil M, Zhang X, Claessen N, Butter L, van Stalborch AD, Florquin S, van Buul JD, Tammaro A, Roelofs JJTH.   +9 more
europepmc   +1 more source

Endothelial Dysfunction: Insights into Systemic Lupus Erythematosus-associated Cardiovascular Disease and Neuropsychiatric Manifestations. [PDF]

J Cardiovasc Transl Res
Butler HM, Zehntner ME, Van Beusecum JP.
europepmc   +1 more source

Chia Oil Supplementation Attenuates Obesity-Induced Hepatic Steatosis, PVAT Inflammation, and Endothelial Dysfunction in Mice. [PDF]

Mol Nutr Food Res
de Assis-Ferreira A, Muniz-Cassuce G, Fonte-Faria T, de Souza T, Citelli M, de Carvalho LCRM, Ognibene DT, de Bem GF, Resende AC, Barja-Fidalgo C, Vargas da Silva S.   +10 more
europepmc   +1 more source

Endothelial dysfunction markers in cervical cancer and their influence on patient outcome. [PDF]

Mol Biol Rep
Raeck J, da Silva JB, Carvalho L, Salgado L, Pereira D, Neto BV, Tavares V, de Melo IG, Medeiros R.   +8 more
europepmc   +1 more source

Endothelial Dysfunction in Atherosclerosis: Experimental Models and Therapeutics. [PDF]

Biomater Res
Kopych V, Da Costa ADS, Park K.
europepmc   +1 more source