Results 251 to 260 of about 1,271,424 (340)

Development of a Modular Ribonucleoprotein Complex as a General Strategy to Deliver RNAi Therapeutics

Advanced Healthcare Materials, EarlyView.
A modular and customizable RNAi therapeutics delivery platform composed of a pseudosymmetric human RNA binding protein‐siRNA complex (SmiRNP) is developed. By fusing a targeting module and an endosomal escape peptide onto the delivery platform, SmiRNP successfully delivered siRNA to silence the KRAS oncogene in a colorectal carcinoma cell line, leading
Nok Yin Tam, Xiaoqi Wang, Grace Chung Yan Chan, Wai Po Kong, Wai Yin Chau, Xiuqiong Fu, Kwok‐Yin Wong, Hong Lok Lung, Zhi‐Ling Yu, Wei Shen Aik   +9 more
wiley   +1 more source

Single-cell dynamic RNA and glycosylation sequencing reveals the mechanism underlying the differentiation of pluripotent stem cells into hematopoietic stem cells. [PDF]

Hum Cell
Feng W, Zeng S, Liu D, Gong W, Hu J, Xu W, Ma Z, Fu S, Chen X.   +8 more
europepmc   +1 more source

Signalling pathways that regulate endothelial differentiation from stem cells [PDF]

, 2010
Zhenling Luo
openalex   +1 more source

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

Advanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang, Sílvio Terra Stefanello, Victor Shahin, Yun Qian   +3 more
wiley   +1 more source

In vitro biomimetic models for respiratory diseases: progress in lung organoids and lung-on-a-chip. [PDF]

Stem Cell Res Ther
Zhang X, Liu H, Cheng H, Cui Y, Wang J, Yao Q, Wang P, Hu Y, Wang Y.   +8 more
europepmc   +1 more source

e0144 The efficacy of transplantation of mesenchymal stem cells with gelatin microspheres containing vascular endothelial growth factor in ischaemic regions [PDF]

, 2010
Qiong Liu, Shihua Zhao, Shiliang Jiang, Lu Minjie, Li Jian, Yan Zhou, Chaowu Yan, Huaibing Cheng, Man Ning, L. Shiguo, Y. Gang   +10 more
openalex   +1 more source

Vascularized and Perfusable Human Heart‐on‐a‐Chip Model Recapitulates Aspects of Myocardial Ischemia and Enables Analysis of Nanomedicine Delivery

Advanced Materials, EarlyView.
This novel 3D human ischemic heart‐on‐a‐chip, with perfusable vasculature directly interfaced with myocardial tissue, replicates key aspects of ischemic heart injury. It also demonstrates the targeted delivery and therapeutic efficacy of cardiac homing peptide‐conjugated liposomes, validating the platform for drug and nanomedicine screening in ...
Junyoung Kim, Xuening Zhang, Richard Wang, Adrian Najer, Qiao You Lau, Ana Cammack‐Najera, Jang Ah Kim, Yoo Kyung Kang, Ruoxiao Xie, Hyemin Kim, Kai Xie, Hyeonji Lim, Tae‐Eun Park, Jinmyoung Joo, Molly M. Stevens   +14 more
wiley   +1 more source

Current status and advances in adipose-derived stem cells therapy for diabetes mellitus erectile dysfunction. [PDF]

Front Med (Lausanne)
Liu J, Jiang T.
europepmc   +1 more source

Plaque‐Targeted Delivery of Fluoride‐Free MXene Nanozyme for Alleviating Atherosclerosis via Sonocatalytic Therapy

Advanced Materials, EarlyView.
This work has developed a dual enzyme‐mimicking and ultrasound‐responsive Nb2C‐Pt@HA‐PEG nanozyme. ROS‐eliminating and anti­inflammatory capability of Nb2C‐Pt@HA‐PEG under US irradiation are demonstrated on macrophages and endothelial cells in vitro. Nb2C‐Pt@HA‐PEG‐mediated sonocatalytic therapy exerts an outstanding anti‐atherosclerosis efficacy by ...
Qianqian Bai, Xinyue Lao, Sin‐Yi Pang, Yifei Zhao, Yuan Liu, Xiao Yu Tian, Jianhua Hao   +6 more
wiley   +1 more source

Single-cell transcriptomics identifies PDGFRA⁺ progenitors orchestrating angiogenesis and periodontal tissue regeneration. [PDF]

Int J Oral Sci
Liu J, He J, Zhang Z, Liu L, Cao Y, Zhang X, Cai X, Luo X, Lei X, Zhang N, Wang H, Chen J, Liu P, Tian J, Liu J, Gao Y, Xu H, Ma C, Bai S, Zhang Y, Jin Y, Zheng C, Sui B, Jin F.   +23 more
europepmc   +1 more source