Results 151 to 160 of about 23,747,035 (396)
A review of sitaxsentan sodium in patients with pulmonary arterial hypertension
Vascular Health and Risk Management, 2007 Aaron B WaxmanDepartment of Internal Medicine, Pulmonary Critical Care Unit, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USAAbstract: Pulmonary arterial hypertension (PAH) is a life threatening, progressive condition which ...
Aaron B Waxman
doaj
Medicine Bulletin, EarlyView.ABSTRACT Background Balloon pulmonary angioplasty (BPA) has emerged as an effective treatment for chronic thromboembolic pulmonary hypertension (CTEPH). Recent studies have reported progressive improvements in hemodynamic and clinical parameters during follow‐up, even without additional interventions.
Wenjie Dong +8 more
wiley +1 more source
Molecular Nutrition &Food Research, EarlyView.(Poly)phenols constitute a source of natural therapeutic molecules capable of targeting angiogenesis in different scenarios. This review summarizes the current evidence of the role of (poly)phenols in modulating angiogenesis. The reader can find a compilation of preclinical and human investigations describing pro‐ and anti‐angiogenic effects of these ...
María Ángeles Ávila‐Gálvez +5 more
wiley +1 more source
History of pre‐eclampsia negatively impacts stroke severity postpartum in rats
Neuroprotection, EarlyView.Diagrammatic representation of the effect of pre‐eclampsia on postpartum stroke severity. e7, gestational day 7; ePE, experimental pre‐eclampsia; NormP, normal pregnancy; PP, postpartum; tMCAO, transient middle cerebral artery occlusion. Made in Biorender.
Ari Kropf +4 more
wiley +1 more source
Chronic ETA receptor blockade prevents endothelial dysfunction of small arteries in apolipoprotein E-deficient mice [PDF]
, 2017 Objective: This study investigated whether endothelial dysfunction occurs in mesenteric arteries of apoE-deficient mice and determined the role of endothelin (ET)-1, which is increased in human atherosclerosis, using an orally active endothelin ETA ...
Barton, Matthias +3 more
core
Efficient Regioselective Iodination of Pyrazole Derivatives Mediated by Cadmium(II) Acetate
ChemistryOpen, EarlyView.The iodination reactions of both N, C alkyl‐, propargylic substituted and unsubstituted pyrazole derivatives initiated by cadmium (II) acetate were performed. It was revealed that the C‐4 position of the pyrazole ring was more nucleophilic. The nucleophilicity of the pyrazole ring significantly increased due to the influence of alkyl groups and ...
Nina G. Hobosyan +8 more
wiley +1 more source
Frontiers in PhysiologyBackgroundResistance of voiding symptoms to α1-blockers in benign prostatic hyperplasia (BPH) has been provisionally explained by non-adrenergic prostate smooth muscle contraction. Here, we examined relationships between contractions and voiding symptoms
Patrick Keller +7 more
doaj +1 more source
Endothelin‐1 Stimulates Monocytes in vitro to ReleaseChemotactic Activity Identified as Interleukin‐8 and Monocyte Chemotactic Protein‐1 [PDF]
, 1994 E. Helset +2 more
openalex +1 more source
Pharmacotherapy for Cirrhosis in Japan
Portal Hypertension &Cirrhosis, EarlyView.As cirrhosis progresses from the compensated to the decompensated stage, liver disease‐related events such as varices, ascites, encephalopathy, sarcopenia, jaundice, and bleeding tendency, as well as liver carcinogenesis, can occur at a high rate. With the advent of new pharmacotherapies for cirrhosis in the last decade, liver fibrosis has been shown ...
Hiroki Nishikawa, Soo Ki Kim, Akira Asai
wiley +1 more source