Results 161 to 170 of about 24,309,158 (381)

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Endothelin-1 in exhaled breath condensate of allergic asthma patients with exercise-induced bronchoconstriction [PDF]

, 2007
Ziemowit Ziętkowski, Roman Skiepko, Maria Magdalena Tomasiak, Anna Bodzenta­‐Łukaszyk   +3 more
openalex   +1 more source

Resistance exercise breaks during prolonged sitting augment the blood flow response to a subsequent oral glucose load in sedentary adults

Experimental Physiology, EarlyView.
Abstract Sitting‐induced impairments in postprandial blood flow are an important link between sedentary behaviour and cardiometabolic disease risk. The objective of this work was to examine the effects of resistance exercise breaks (REB) performed every 30 min during an otherwise sedentary 3‐h period on the vasodilatory response to a subsequent oral ...
Emily M. Rogers, Nile F. Banks, Emma R. Trachta, Morgan S. Wolf, Alexander C. Berry, Anna E. Stanhewicz, Lucas J. Carr, Bethany Barone Gibbs, Nathaniel D. M. Jenkins   +8 more
wiley   +1 more source

P27 Expression in Endothelin-1 Stimulated Mitogenesis [PDF]

, 2007
Bovine corneal endothelial cells (BCECs) have been shown in our lab to synthesize and secrete endothelin-1 (ET-1). The endothelin-1 binds ETA receptors, this elevates intracellular calcium, stimulate DNA replication and cell division.
Kiriu, Joseph
core   +1 more source

Voiding symptom severity varies independently from non-adrenergic prostate smooth muscle contractions in patients undergoing surgery for benign prostatic hyperplasia

Frontiers in Physiology
BackgroundResistance of voiding symptoms to α1-blockers in benign prostatic hyperplasia (BPH) has been provisionally explained by non-adrenergic prostate smooth muscle contraction. Here, we examined relationships between contractions and voiding symptoms
Patrick Keller, Sheng Hu, Philip Nicola, Laurenz Berger, Alexander Tamalunas, Philipp Weinhold, Christian G. Stief, Martin Hennenberg   +7 more
doaj   +1 more source

Intrarenal activation of endothelin type B receptors improves kidney oxygenation in type 1 diabetic rats [PDF]

, 2017
Stephanie Franzén, Liselotte Pihl, Angelica Fasching, Fredrik Palm   +3 more
openalex   +1 more source

Vascular health and exercise in females throughout the lifespan: Exploring puberty, pregnancy and menopause

Experimental Physiology, EarlyView.
Abstract This narrative review highlights the impact of exercise on vascular health in females over the lifespan with an emphasis on puberty, pregnancy and menopause. These events encompass substantial changes in sex hormone levels, particularly oestrogens and progesterone.
Kathleen B. Miller, M. Erin Moir, Brandon G. Fico   +2 more
wiley   +1 more source

The Role of NOX2-Derived Reactive Oxygen Species in the Induction of Endothelin-Converting Enzyme-1 by Angiotensin II [PDF]

Michael Adu Gyamfi, Claudia Goettsch, Julian Kamhieh‐Milz, Lei Chen, Anna Maria Pfefferkorn, Anja Hofmann, Coy Brunßen, Gregor Müller, Thomas Walther, Muhammad Imtiaz Ashraf, Henning Morawietz, Janusz Witowski, Rusan Catar   +12 more
openalex   +1 more source

Overproduction of endothelin-1 impairs glucose tolerance but does not promote visceral adipose tissue inflammation or limit metabolic adaptations to exercise [PDF]

, 2019
Thomas J. Jurrissen, Zachary I. Grunewald, Makenzie L. Woodford, Nathan C. Winn, James R. Ball, Thomas N. Smith, Andrew A. Wheeler, Arthur Rawlings, Kevin F. Staveley-O’Carroll, Yan Ji, William P. Fay, Pierre Paradis, Ernesto L. Schiffrin, Victoria J. Vieira‐Potter, Paul J. Fadel, Luis A. Martinez‐Lemus, Jaume Padilla   +16 more
openalex   +1 more source

The therapeutic role of exercise training during menopause for reducing vascular disease

Experimental Physiology, EarlyView.
Abstract Menopause marks a major milestone in female reproductive ageing. It is characterized by the cessation of ovarian function and a concomitant decline in hormones such as oestradiol. Subsequently, females undergoing menopausal transition experience a progressive increase in cardiovascular and cerebrovascular disease risk.
Conan L. H. Shing, Bert Bond, Kerrie L. Moreau, Jeff S. Coombes, Jenna L. Taylor   +4 more
wiley   +1 more source