Results 11 to 20 of about 23,747,035 (396)
Endothelin-1 and antiangiogenesis. [PDF]
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2016 Antiangiogenesis, targeting vascular endothelial growth factor (VEGF), has become a well-established treatment for patients with cancer. This treatment is associated with nitric oxide (NO) suppression and a dose-dependent activation of the endothelin ...
S. Lankhorst +2 more
semanticscholar +4 more sources
Endothelin-1 in systemic sclerosis
Indian Dermatology Online Journal, 2012 Introduction: Scleroderma is a systemic disorder with unknown etiology most notably characterized by skin thickening and organ damage. Endothelin-1 (ET-1) plays a role in skin fibrosis.
Mehrdad Aghaei +7 more
doaj +4 more sources
Endothelin-1 in systemic sclerosis
Reumatismo, 2011 We evaluated endothelin-1 (ET-1) plasma levels in patients affected by primary Raynaud’s phenomenon (PRP), as well as in patients with systemic sclerosis (SSc) and secondary Raynaud’s phenomenon (SRP).
C. Pizzorni +3 more
doaj +7 more sources
The role of endothelin-1 in pulmonary arterial hypertension [PDF]
Global Cardiology Science & Practice, 2014 Pulmonary arterial hypertension (PAH) is a rare but debilitating disease, which if left untreated rapidly progresses to right ventricular failure and eventually death. In the quest to understand the pathogenesis of this disease differences in the profile,
A. Chester, M. Yacoub
semanticscholar +3 more sources
Endocan, ET-1, and ETAR Expression Profiles in Unicystic Ameloblastoma, Multicystic Ameloblastoma, and Ameloblastic Carcinoma [PDF]
Middle East Journal of Cancer, 2019 Background: Odontogenic lesions range from simple cysts to benign tumors and carcinomas. Unicystic ameloblastoma is a monocystic lesion and a less aggressive tumor compared to multicystic ameloblastoma.
Soussan Irani, Zhaleh Mohsenifar
doaj +1 more source
Immunohistochemical Localization of Endothelin- 1 and Endothelin A Receptor in Human Primary Tooth Enamel Organ [PDF]
Journal of Dentistry, 2023 Statement of the Problem: Enamel organ (EO) is an ectodermal derived structure, which is involved in the different aspects of tooth development. Tooth development shares the same regulatory molecules and genes expressed in other developing organs ...
Soussan Irani +2 more
doaj +1 more source
Production of endothelin‐1 and big‐endothelin‐1 by pleural mesothelial cells [PDF]
FEBS Letters, 1992 Immunoreactive endothelin‐1 (ET‐1) and big‐endothelin‐1 (big‐ET‐1) were detected in conditioned medium of cultured rat pleural mesothelial cells by using sensitive sandwich‐type enzyme immunoassays. The amount of both ET‐1 and big‐ET‐1 increased time‐dependently. In both instances, maximal amount was detectable in conditioned medium obtained after 72 h
Maki Kuwahara +2 more
openaire +2 more sources
Analiz Riska Zdorovʹû, 2021 Our research goal was to reveal peculiarities related to changes in endothelin-1 contents in blood serum in young and middle-aged people exposed to occupational noise and industrial welding and silicon-containing aerosols with fibrogenic effects. Another
I.A. Umnyagina +5 more
doaj +1 more source
Analysis of Endothelin-1 Concentrations in Individuals with Periodontitis
Scientific Reports, 2020 Endothelin 1 (ET-1) has been shown to have a key role in homeostasis and function of endothelium and maybe fundamental in the relationship between coronary heart disease (CHD) and periodontitis.
G. Isola +4 more
semanticscholar +1 more source
Endothelin-1 (1-31) Is an Intermediate in the Production of Endothelin-1 After Big Endothelin-1 Administration In Vivo [PDF]
Hypertension, 2005 The precursor of endothelin-1, big endothelin-1, can be hydrolyzed by chymase to generate endothelin-1 (1-31) in vitro. In the present study, we explored the processes involved in the production of endothelin-1 (1-31) as well as its pharmacodynamic characteristics in the rabbit in vivo.
Julie Labonté +5 more
openaire +3 more sources