Results 31 to 40 of about 21,304,051 (308)

Endothelin in health and disease

Biomolecules & Biomedicine, 2004
Endothelin is a recently discovered peptide composed of 21 amino acids. There are three endothelin isomers: endothelin -1 (ET-1), endothelin -2 (ET-2) and endothelin - 3 (ET-3).
Emina Nakaš-Ićindić, Asija Začiragić, Almira Hadžović, Nešina Avdagić   +3 more
doaj   +1 more source

Evaluation of the Expression Levels of Endothelin-1 and its Receptor (ETAR) in Dental Lamina during Different Stages of Development of Human Fetal Teeth

پزشکی بالینی ابن سینا, 2021
Background and Objective: Due to the significant importance of the teeth in mastication, speech, and aesthetics, it is necessary to identify all involved genes in the tooth development. Therefore, this study aimed to evaluate the role of endothelin-1 and
Soussan Irani, Shohreh Alimohammadi, Tahmineh Najafian   +2 more
doaj  

Umbilical cord blood and neonatal endothelin-1 levels in preterm newborns with and without respiratory distress syndrome

Brazilian Journal of Medical and Biological Research, 2005
Increased pulmonary vascular resistance in preterm newborn infants with respiratory distress syndrome is suggested, and endothelin-1 plays an important role in pulmonary vascular reactivity in newborns.
A.C.W. Benjamin, R.C. Silveira, R.S. Procianoy   +2 more
doaj   +1 more source

Endothelium-derived endothelin-1 [PDF]

Pflügers Archiv - European Journal of Physiology, 2009
One year after the revelation by Dr. Furchgott in 1980 that the endothelium was obligatory for acetylcholine to relax isolated arteries, it was clearly shown that the endothelium could also promote contraction. In 1988, Dr. Yanagisawa's group identified endothelin-1 (ET-1) as the first endothelium-derived contracting factor.
Thorin, Eric, Webb, David J.
openaire   +3 more sources

Hemodynamic and inotropic effects of endothelin-1 in vivo

, 1994
Endothelin-1 (ET-1) is known to have strong vasoactive properties. Contradictory results have been reported with regard to its inotropic effects. This study examined the dose-dependent (500, 1000, 2500, 5000 and 10,000 ng ET-1/kg vs.
Beyer, M. E., Hoffmeister, H. M., Krämer, Bernhard K., Nerz, S.   +3 more
core   +1 more source

Endothelin-1 contributes to the development of virus-induced demyelinating disease

Journal of Neuroinflammation, 2020
Background Experimental autoimmune encephalitis (EAE) and virally induced demyelinating disease are two major experimental model systems used to study human multiple sclerosis.
Young-Hee Jin, Bongsu Kang, Hyun S. Kang, Chang-Sung Koh, Byung S. Kim   +4 more
doaj   +1 more source

Myocardial ischemia-reperfusion enhances transcriptional expression of endothelin-1 and vasoconstrictor ETB receptors via the protein kinase MEK-ERK1/2 signaling pathway in rat. [PDF]

PLoS ONE, 2017
BACKGROUND:Coronary artery remodelling and vasospasm is a complication of acute myocardial ischemia and reperfusion. The underlying mechanisms are complex, but the vasoconstrictor peptide endothelin-1 is suggested to have an important role.
Gry Freja Skovsted, Lars Schack Kruse, Lukas Adrian Berchtold, Anne-Sofie Grell, Karin Warfvinge, Lars Edvinsson   +5 more
doaj   +1 more source

Endothelin-1 Production by Normal Human Cultured Keratinocytes and its Regulation

Mediators of Inflammation, 1994
The possibility that cultured keratinocytes produce endothelins were investigated. The results showed that cultured keratinocytes derived from normal human skin produce endothelin-1. Moreover, keratinocyte endothelin-1 production was completely inhibited
Hajime Inoue, Nagaoki Wakisaka, Nobuhiro Tane, Kazumasa Ando, Emiko Isono, Miwa Yamanaka, Masaki Aihara, Hirotomo Ishida   +7 more
doaj   +1 more source

Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts

, 2004
The endothelins are a family of endothelium-derived peptides that possess a variety of functions, including vasoconstriction. Endothelin-1 (ET-1) is up-regulated during tissue repair and promotes myofibroblast contraction and migration, hence ...
Abraham, DJ, du Bois, R M, Denton, CP, Black, C M, Chen, YL, Chen, Y L, Chen, Y, Shi-Wen, X., Renzoni, E.A., Denton, C P, Shi-Wen, X, Leask, A., Pearson, J D, Xu, SW, Bou-Gharios, George, du Bois, RM, Xu, S W, Dashwood, M, Denton, C.P., Bou-Gharios, G., Renzoni, E A, Pearson, JD, Chen, Y., Abraham, D.J., Abraham, D J, Renzoni, EA, Black, CM, Dashwood, M., Eastwood, M, Leask, A, Eastwood, M., Black, C.M., Pearson, J., du Bois, R., Bou-Gharios, G   +34 more
core   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source