Results 31 to 40 of about 29,698,280 (59)
Endothelin-1 (ET-1) acts as a key mediator of vasoconstriction and tissue repair. Overproduction of connective tissue growth factor (CTGF) underlies the development of lung fibrosis. ET-I induces expression of matrix-associated genes in lung fibroblasts,
郭明良 +1 more
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Endothelin-1 release by endothelial cells stimulated with B2R and D2R agonists.
Confluent cell cultures were preincubated with 10 ng/ml TNF-α for 6 hours, followed by stimulation with 100 nM BK, 100 nM SUM, or both agonists simultaneously for 24 hours and the ET-1 concentration was measured by ELISA. The bars present the mean values
Andrzej Kozik (5963546) +2 more
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Effects of magnesium treatment in a model of internal capsule lesion in spontaneously hypertensive rats [PDF]
<p><b>Background and Purpose:</b> The study aim was to assess the effects of magnesium sulfate (MgSO4) administration on white matter damage in vivo in spontaneously hypertensive rats.</p> <p><b>Methods:</b> ...
McCabe, C. +8 more
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Rescue with an anti-inflammatory peptide of chickens infected H5N1 avian flu [PDF]
Chickens suffering from avian flu caused by H5N1 influenza virus are destined to die within 2 days due to a systemic inflammatory response. Since HVJ infection (1,2) and influenza virus infection (3,4) cause infected cells to activate homologous serum ...
Noriko N. Okada +7 more
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Atherosclerosis is the primary ischaemic vascular condition underlying a majority of cardiovascular disease related deaths. Endothelin-1 is a vasoactive peptide agent upregulated in atherosclerosis and in conjunction with its G protein-coupled receptors ...
Peter Little AM (18043684) +2 more
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Endothelin-1 in the regulation of vascular function and glucose metabolism in insulin resistance
Insulin resistance plays a major role in the pathogenesis of type 2 diabetes and is an important risk factor for cardiovascular disease. Endothelial dysfunction, characterized by reduced bioactivity of nitric oxide and increased activity of the ...
Alexey Shemyakin (18663223)
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Efeitos da endotelina-1 nos ductos biliares extra-hepático e no esfíncter de Oddi isolados de cobaia [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências BiológicasEste estudo procurou avaliar os efeitos da [endotelina-1] (ET-1) na motilidade de diferentes porções do trato biliar extra-hepático isolado de cobaia.
Koepp, Janice
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The importance of endothelin-1 for microvascular dysfunction in diabetes
Majid KalaniDepartment of Clinical Sciences Karolinska Institutet, Dept of Cardiology, Danderyd Hospital, Stockholm, SwedenAbstract: Most of the late diabetic complications such as retinopathy, nephropathy, and neuropathy, have their basis in disturbed ...
Majid Kalani, Kalani, M,
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Endothelin-1 and endothelin-4 stimulate monocyte production of cytokines
OBJECTIVE: To determine the effect of endothelin-1 and endothelin-4 on human monocyte production of cytokines. DESIGN: Previous work from our laboratory has shown that endothelin-1 activates leukocytes.
Huribal, M +3 more
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Plasma endothelin-1 as screening marker for cerebral vasospasm after subarachnoid hemorrhage
Cerebral vasospasm complicating subarachnoid hemorrhage causes ischemic stroke and worsens the neurological outcome. The potential role of endothelin-1 in vasospasm pathogenesis may provide therapeutic opportunities.
Boots, R. +3 more
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