Immunohistochemical Localization of Endothelin- 1 and Endothelin A Receptor in Human Primary Tooth Enamel Organ [PDF]
Journal of Dentistry, 2023 Statement of the Problem: Enamel organ (EO) is an ectodermal derived structure, which is involved in the different aspects of tooth development. Tooth development shares the same regulatory molecules and genes expressed in other developing organs ...
Soussan Irani +2 more
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Frontiers in Immunology, 2023 Major Histocompatibility Complex (MHC) molecules have been proposed to play a role in Sickle Cell Disease (SCD) pathophysiology. Endothelial cells express MHC molecules following exposure to cytokines.
Yaritza Inostroza-Nieves +6 more
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Serum endothelin-1 level positively correlates with waist and hip circumferences in stable coronary artery disease patients [PDF]
Reviews in Cardiovascular Medicine, 2021 Central obesity is associated with increased level and activity of endothelin-1. The waist and hip circumferences are simple indicators of central obesity.
Anggoro Budi Hartopo +3 more
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The dual endothelin converting enzyme/neutral endopeptidase inhibitor SLV-306 (daglutril), inhibits systemic conversion of big endothelin-1 in humans [PDF]
, 2012 Aims - Inhibition of neutral endopeptidases (NEP) results in a beneficial increase in plasma concentrations of natriuretic peptides such as ANP.
Johnston, F. +26 more
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Endothelin-1 is associated with fibrosis in proliferative diabetic retinopathy membranes. [PDF]
PLoS ONE, 2018 To characterize the relationship between endothelin-1 and fibrosis in epiretinal membranes in proliferative diabetic retinopathy and explore the role of endothelial-mesenchymal transition in these membranes.Membranes were obtained from eyes undergoing ...
William Chang +2 more
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Production of endothelin‐1 and big‐endothelin‐1 by pleural mesothelial cells
FEBS Letters, 1992 Immunoreactive endothelin‐1 (ET‐1) and big‐endothelin‐1 (big‐ET‐1) were detected in conditioned medium of cultured rat pleural mesothelial cells by using sensitive sandwich‐type enzyme immunoassays. The amount of both ET‐1 and big‐ET‐1 increased time‐dependently. In both instances, maximal amount was detectable in conditioned medium obtained after 72 h
Kuwahara, Masayoshi +2 more
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Comparison of haemoconcentration induced by big endothelin‐1 and endothelin‐1 in mice [PDF]
British Journal of Pharmacology, 1993 The profile of haemoconcentration induced by big endothelin‐1 (big ET‐1), a precursor of endothelin‐1 (ET‐1), was compared with that induced by endothelin‐1 in mice. ET‐1(1.5 nmol kg−1, i.v.) increased haematocrit in mice, which reached a maximum at 5 min and then returned to the control value within 30 min after the administration, this occurred at ...
H, Okumura +6 more
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Endocrine and Metabolic Science, 2023 Introduction: African Americans (AAs) have the highest prevalence of hypertension among United States racial/ethnic groups. Regulators of blood pressure, such as aldosterone and endothelin-1, impact glucose regulation.
Joshua J. Joseph +7 more
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Endothelin and increased contractility in adult rat ventricular myocytes. Role of intracellular alkalosis induced by activation of the protein kinase C-dependent Na(+)-H+ exchanger [PDF]
, 1991 Endothelin, a 21-amino acid vasoactive peptide, is among the most potent positively inotropic agents yet described in mammalian heart. Having demonstrated that endothelin's inotropic effect is due, in part, to an apparent sensitization of cardiac ...
Smith, T. W. +2 more
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Endothelin-converting enzyme-1 expression in acute and chronic liver injury in fibrogenesis
Animal Cells and Systems, 2019 Endothelin-1 (ET-1) induces contraction, proliferation, and collagen synthesis of activated hepatic stellate cells and is a potent mediator of portal hypertension.
Tae-Jun Cho, Hyo-Jung Kim, Jaejin Cho
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