Results 101 to 110 of about 90,498 (305)

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Endothelin and vasopressin influence splanchnic blood flow distribution during and after cardiopulmonary bypass [PDF]

, 2012
Hagen Bomberg, Benjamin Bierbach, Stephan Flache, Isabell Wagner, Lena Gläser, Heinrich V. Groesdonk, Michael D. Menger, Hans‐Joachim Schäfers   +7 more
openalex   +1 more source

Resistance exercise breaks during prolonged sitting augment the blood flow response to a subsequent oral glucose load in sedentary adults

Experimental Physiology, EarlyView.
Abstract Sitting‐induced impairments in postprandial blood flow are an important link between sedentary behaviour and cardiometabolic disease risk. The objective of this work was to examine the effects of resistance exercise breaks (REB) performed every 30 min during an otherwise sedentary 3‐h period on the vasodilatory response to a subsequent oral ...
Emily M. Rogers, Nile F. Banks, Emma R. Trachta, Morgan S. Wolf, Alexander C. Berry, Anna E. Stanhewicz, Lucas J. Carr, Bethany Barone Gibbs, Nathaniel D. M. Jenkins   +8 more
wiley   +1 more source

Rolle des Endothelin-Systems bei den Interaktionen der pressorischen Systeme in der Wirkung auf den Gefäßtonus in vivo beim Menschen: Bedeutung von genetischen Wirtsfaktoren

, 2021
Bastian Brune
openalex   +1 more source

Vascular health and exercise in females throughout the lifespan: Exploring puberty, pregnancy and menopause

Experimental Physiology, EarlyView.
Abstract This narrative review highlights the impact of exercise on vascular health in females over the lifespan with an emphasis on puberty, pregnancy and menopause. These events encompass substantial changes in sex hormone levels, particularly oestrogens and progesterone.
Kathleen B. Miller, M. Erin Moir, Brandon G. Fico   +2 more
wiley   +1 more source

Endothelin receptor antagonists (ERAs) can potentially be used as therapeutic drugs to reduce hypertension caused by small molecule tyrosine kinase inhibitors (TKIs)

Frontiers in Pharmacology
The emergence of targeted anti-tumor drugs has significantly prolonged the lifespan and improved the prognosis of cancer patients. Among these drugs, vascular endothelial growth factor (VEGF) inhibitors, particularly novel small molecule tyrosine kinase ...
Qingjian He, Junling Lin, Chanjuan Mo, Guodong Li, Jianzhong Lu, Qiyin Sun, Lijun Cao, Haojian Gan, Quan Sun, Jiafang Yao, Shengyi Lian, WenJuan Wang   +11 more
doaj   +1 more source

The Role of NOX2-Derived Reactive Oxygen Species in the Induction of Endothelin-Converting Enzyme-1 by Angiotensin II [PDF]

Michael Adu Gyamfi, Claudia Goettsch, Julian Kamhieh‐Milz, Lei Chen, Anna Maria Pfefferkorn, Anja Hofmann, Coy Brunßen, Gregor Müller, Thomas Walther, Muhammad Imtiaz Ashraf, Henning Morawietz, Janusz Witowski, Rusan Catar   +12 more
openalex   +1 more source

Serum endothelin concentrations in workers exposed to vibration. [PDF]

, 1996
K. T. Palmer, H Mason
openalex   +1 more source

The therapeutic role of exercise training during menopause for reducing vascular disease

Experimental Physiology, EarlyView.
Abstract Menopause marks a major milestone in female reproductive ageing. It is characterized by the cessation of ovarian function and a concomitant decline in hormones such as oestradiol. Subsequently, females undergoing menopausal transition experience a progressive increase in cardiovascular and cerebrovascular disease risk.
Conan L. H. Shing, Bert Bond, Kerrie L. Moreau, Jeff S. Coombes, Jenna L. Taylor   +4 more
wiley   +1 more source

Ischemic heart disease induce upregulation of endothelin receptor mRNA in human coronary arteries

, 2003
Angelica Wackenfors, Malin Emilson, Richard Ingemansson, Tibor Hortobágyi, Délia Szok, János Tajti, László Vécsei, Lars Edvinsson, Malin Malmsjö   +8 more
openalex   +2 more sources