Results 131 to 140 of about 63,830 (268)

Big Endothelin-1 Predicts the long-term survival in patients undergoing septal myectomy. [PDF]

Int J Cardiol Heart Vasc
Song C, Huang X, Cui J, Zheng X, Yang Q, Wang S.   +5 more
europepmc   +1 more source

Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions

MedComm, Volume 7, Issue 7, July 2026.
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An, Yi An, Mengwei Chen, Longlong Wu, Rong Wang   +4 more
wiley   +1 more source

Role for endothelin-1 in cardiometabolic dysfunction with intermittent hypoxia. [PDF]

Function (Oxf)
Gonsalves AM, Baker SE, Singh P, Limberg JK.   +3 more
europepmc   +1 more source

Endothelin in renal disease: role of endothelin antagonists [PDF]

Nephrology Dialysis Transplantation, 1995
T F, Lüscher, R R, Wenzel
openaire   +2 more sources

Endoplasmic reticulum stress and the unfolded protein response in lung diseases: molecular pathways and therapeutic interventions

The Journal of Pathology, Volume 269, Issue 3, Page 268-283, July 2026.
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song, Yichen Liu, Chen Xu, Yaochen Zhang, Kaiming Xu, Dan Yao, Xiaoying Huang   +6 more
wiley   +1 more source

Activin A-Endothelin-1 Axis Governs Pulmonary Vascular Remodeling: Mechanistic Basis for Emerging Therapies in PAH. [PDF]

Arterioscler Thromb Vasc Biol
Faizah NN, Ryanto GRT, Kencana SMS, Suzuki Y, Hara T, Otake H, Emoto N.   +6 more
europepmc   +1 more source

Protein and Peptide Inhibitors of Mineralization: A Systematic Review of In Vitro Studies

Journal of Peptide Science, Volume 32, Issue 7, July 2026.
In vitro evidence from crystallization assays demonstrates that peptides inhibit mineral nucleation and crystal growth through sequence‐dependent interactions (acidic residues and phosphorylation) with mineral surfaces. In cell cultures, these molecules reduce calcium deposition and ALP activity and modulate the expression of biomineralization‐related ...
Alberto Mimila‐Cortes, Lucia Méndez‐Sánchez, Luis Fernando Ramírez‐González, Lia Hoz‐Rodríguez, Maricela Santana‐Vázquez, Karen Ivette Castro‐López, Higinio Arzate, Gonzalo Montoya‐Ayala   +7 more
wiley   +1 more source

Crataegus oxyacantha Extract Enhances Cardiac Adaptation and Reduces Oxidative‐Inflammatory Stress in Broiler Chickens Raised at High Altitude Under Cold Stress

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Crataegus oxyacantha extract at 0.4 mL/L improved cardiac function in broilers under cold stress and high altitude by increasing nitric oxide synthase gene expression, boosting nitric oxide, reducing endothelin‐1 gene expression, and lowering oxidative‐inflammatory stress, offering a natural solution to mitigate pulmonary hypertension syndrome ...
Behnam Ahmadipour, Hossein Hassanpour, Samira Abaszadeh, Majid Kalantar   +3 more
wiley   +1 more source

Association between endothelin-1 and diabetic retinopathy: a systematic review and meta-analysis. [PDF]

Front Endocrinol (Lausanne)
Sun X, An Y, Zeng X, Jiang Y.
europepmc   +1 more source

Endothelial Netrin‐4 regulates oligodendrocyte precursor cell proliferation and differentiation via ET‐1 signaling in preterm white matter injury

Brain Pathology, Volume 36, Issue 4, July 2026.
Our findings show early increased Netrin‐4 in mice with PWMI boosts angiogenesis and OPCs proliferation. Later, high levels hinder OPCs differentiation into mature cells, impairing myelination. It may act by stimulating ET‐1 secretion. Abstract Perinatal hypoxia–ischemia is a leading cause of preterm white matter injury (PWMI), yet mechanisms ...
Fuxing Dong, Weixing Yan, Qiqi Meng, Xueli Song, Bing Cheng, Yaping Liu, Yanan Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source