Results 141 to 150 of about 91,462 (235)

Endothelin Receptor Antagonists in Patients with IgA Nephropathy Treated with Sodium-Glucose Cotransporter 2 Inhibitors. [PDF]

J Am Soc Nephrol
Nachman PH.
europepmc   +1 more source

The acute and chronic effects of local aerobic exercise on cardiovascular physiology

Experimental Physiology, EarlyView.
Abstract Exercise training has beneficial effects for primary and secondary prevention of cardiovascular disease (CVD). Effects of exercise training have typically been studied in the form of whole‐body exercise training, partly driven by the assumption that larger effects of exercise training can be achieved by involving more and larger muscle groups.
Myrthe P. F. van de Ven, Janneke Vloet, Daphne Merkus, Dick H. J. Thijssen   +3 more
wiley   +1 more source

Investigation of the Effects of Switching from Bosentan to Macitentan in Pediatric Pulmonary Hypertension Patients. [PDF]

Sisli Etfal Hastan Tip Bul
Bilen MM, Mese T, Yilmazer MM, Vuran G, Dogan C, Dur YI, Hira O.   +6 more
europepmc   +1 more source

Microvascular endothelial function is blunted in postmenopausal females with frequent hot flushes

Experimental Physiology, EarlyView.
Abstract Hot flushes of menopause are associated with elevated blood pressure (BP) and diminished macrovascular endothelial function, an initiating factor in the onset of atherosclerosis. Whether microvascular endothelial function is impaired in females with hot flushes, however, remains unknown.
William Stokes, Chowdhury Tasnova Tahsin, Miguel F. Anselmo, Stephany Nathe, Emma J. Lee, Soliana Teshome, Marnie L. Vanden Noven, Anne Blaes, Benjamin W. Langworthy, Manda L. Keller‐Ross   +9 more
wiley   +1 more source

Activation of the Endothelin System in Chronic Kidney Disease and Kidney Transplant Recipients-Implications for Disease Progression. [PDF]

Int J Mol Sci
Ściskalska M, Król-Kulikowska M, Grzybowska J, Tabaka E, Pabian W, Pisarek D, Benc K, Kuriata-Kordek M, Banasik M, Kepinska M.   +9 more
europepmc   +1 more source

Leptin–cholesterol crosstalk in pregnancy: Mechanistic implications for placental function and cardiometabolic programming

Experimental Physiology, EarlyView.
Abstract Pregnancy requires the coordinated maternal reorganization of lipid and endocrine pathways to sustain fetal growth and anticipate neonatal nutrition. Leptin, produced by adipose tissue and the placenta, acts as an integrative signal linking maternal energy status with trophoblast function and vascular adaptation, while cholesterol provides ...
Julio Flores, Diego Gumera, Andreina Arias, Cristián A. Amador, María José Yañez   +4 more
wiley   +1 more source

Response by Poudel and Susztak to Letter Regarding Article, "Cell-Specific Inducible Human APOL1 Risk Variant Expression in Mice Causes Hypertension and Renal Damage". [PDF]

Circulation
Poudel B, Susztak K.
europepmc   +1 more source

Optimizing endothelin receptor antagonist use in the management of pulmonary arterial hypertension

, 2008
M Kathryn Steiner1, Ioana R Preston21Pulmonary Critical Care Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA; 2Pulmonary Critical Care and Sleep Division, Department of Medicine, Tufts Medical Center, Boston, MA, USAAbstract:
M Kathryn Steiner, Ioana R Preston
core  

TMEM16A channel signalling microdomains in the regulation of vascular function

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

AI-driven molecular diversification and ligand-based optimization of macitentan derivatives targeting VEGFR1 and endothelin signaling pathways. [PDF]

PLoS One
Sahin SK, Ali N.
europepmc   +1 more source