Results 161 to 170 of about 91,462 (235)

Endothelin-1 Immunoreactivity in plasma is elvated in HIV-1 infected patients with Retinal Microangiopathic syndrome [PDF]

, 1994
Bogner, Johannes R., Klauss, Volker, Rolinski, B., Geier, Stephan A., Sadri, Ifna, Goebel, Frank-Detlef, Ehrenreich, H.   +6 more
core   +1 more source

Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies

The Journal of Physiology, EarlyView.
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu, Rachel E. A. Smyth, Aishwarya Prakash, Thomas Iskratsch   +3 more
wiley   +1 more source

Novel protein biomarkers for risk stratification and personalized medicine. [PDF]

Nephrol Dial Transplant
Moedt E, Ju W, Nair V, Bjornstad P, Kretzler M, Heerspink HJL.   +5 more
europepmc   +1 more source

Predictive Biomarkers in Metastatic Colorectal Cancer Patients Treated With Bevacizumab: A Turkish Oncology Group (TOG) Study

International Journal of Cancer, Volume 159, Issue 8, Page 2075-2083, 15 October 2026.
Bevacizumab added to systemic chemotherapy remains a cornerstone of metastatic colorectal cancer treatment, but its effectiveness is variable. Tumors can bypass the VEGF blockade by activating other pro‐angiogenic pathways, hampering the identification of predictive biomarkers.
Büsra Akay Hacan, Fatma Gizem Sonugür, Müge Öçal, Cansu Babahan, Samira Abgarmi, Ülkü Yalçıntaş Arslan, Mehmet Ali Şendur, Ahmet Demirkazık, Güngör Utkan, Hakan Akbulut   +9 more
wiley   +1 more source

Assessment of generative de novo peptide design methods for G protein-coupled receptors. [PDF]

PLoS One
Junker H, Schoeder CT.
europepmc   +1 more source

Endothelin receptor antagonism for resistant hypertension in chronic kidney disease: where does aprocitentan fit? [PDF]

Clin Kidney J
Stambolliu E, Zoccali C.
europepmc   +1 more source

Development of a population pharmacokinetic model using combined paediatric and adult data for four pulmonary arterial hypertension drugs

British Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3611-3621, October 2026.
Aims Pulmonary arterial hypertension (PAH) is a syndrome characterized by elevated pulmonary artery pressure. We developed a population pharmacokinetic (PPK) model using combined plasma drug concentration data from Japanese paediatric (<15 years) and adult (≥15 years) patients with PAH to investigate the pharmacokinetic characteristics of PAH ...
Motoyasu Miura, Shimako Tanaka, Ririka Aihara, Shun Yamamoto, Yasumi Nakashima, Yasuharu Kashiwagura, Akio Hakamata, Sachiko Miyakawa, Mariko Tatsuguchi, Keiichi Odagiri, Noriyuki Namiki, Naoki Inui, Hiroshi Watanabe, Shinya Uchida   +13 more
wiley   +1 more source

Aprocitentan in resistant hypertension with chronic kidney disease: balancing albuminuria reduction against early volume risk. [PDF]

J Hum Hypertens
Corrêa LMA, Silva YRD, Zanella J, de Santana GC.   +3 more
europepmc   +1 more source

Lung‐Cardiovascular Interactions and Derangements in ARDS

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
This review proposes an anatomical near‐ and far‐field framework for lung‐cardiovascular interactions in ARDS. Grounded in pathological and biological studies, the evidence spans pulmonary vascular, right ventricular, and systemic endothelial derangements and reviews available evidence for targeted therapies.
Pablo A. Sanchez, Connor O'Brien, Matthieu Legrand, Carolyn S. Calfee, Michael A. Matthay   +4 more
wiley   +1 more source

Progress in mechanistic and clinical translational research of endothelin A receptor antagonists in the treatment of diabetic kidney disease: a narrative review. [PDF]

Front Endocrinol (Lausanne)
Li M, Xie C, Qiu Y, Li X, Han G, Ma N, Wang G.   +6 more
europepmc   +1 more source