Results 171 to 180 of about 63,830 (268)

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

Med Research, Volume 2, Issue 2, Page 309-342, June 2026.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

What is the treatment pattern of juvenile systemic sclerosis? Results from an international cohort. [PDF]

J Scleroderma Relat Disord
Foeldvari I, Torok K, Kasapcopur O, Adrovic A, Feldman B, Sztajnbok F, Terreri MT, Sakamoto AP, Johnson S, Anton J, Stanevicha V, Khan A, Schonenberg-Meinema D, Al-Abadi E, Alexeeva E, Katsicas M, Sawhney S, Smith V, Appenzeller S, Avcin T, Kostik M, Lehman T, Malcova H, Marrani E, Pain CE, Patwardhan A, Sifuentes-Giraldo WA, Vasquez-Canizares N, Costa-Reis P, Janarthanan M, Moll M, Nemcova D, Santos MJ, Abu Al-Saoud S, Battagliotti C, Berntson L, Bica B, Brunner J, Eleftheriou D, Harel L, Horneff G, Kaiser D, Kallinich T, Lazarevic D, Minden K, Nielsen S, Nuruzzaman F, Hetlevik SO, Uziel Y, Klotsche J.   +49 more
europepmc   +1 more source

Pharmacology of endothelin.

Japanese Journal of Pharmacology, 1990
openaire   +1 more source

Sympatho‐Excitation in Pulmonary Hypertension: The Potential Role of Pulmonary Arterial Baroreceptors: An Acute Physiologic Intervention Study

Respirology, Volume 31, Issue 6, Page 621-629, June 2026.
Pulmonary arterial baroreceptors reflexively stimulate sympathetic nerve activity (SNA) in response to elevated pulmonary artery pressure and distension. In pulmonary hypertension patients, changes in muscle SNA were proportional to changes in pulmonary haemodynamics following nebulised iloprost.
Michael J. Plunkett, Ana L. C. Sayegh, Robert A. Lewis, Tanya J. McWilliams, Sasiharan Sithamparanathan, Julian F. R. Paton, James P. Fisher   +6 more
wiley   +1 more source

Endothelin-1 upregulates cyclooxygenase-2 expression and prostaglandin E2 synthesis in human periodontal ligament cells-an <i>in vitro</i> study. [PDF]

J Orthod Sci
Unmanatakoon S, Suttamanatwong S.
europepmc   +1 more source

Efficacy of Minimal Blistering Dose‐Based Versus Conventional Excimer Laser Therapy for Vitiligo

The Journal of Dermatology, Volume 53, Issue 6, Page 925-929, June 2026.
ABSTRACT Excimer laser therapy is an established treatment for vitiligo, but the optimal irradiation protocol remains unclear. Irradiation based on the minimal blistering dose (MBD) was recently proposed, but its efficacy relative to conventional protocols has not been systematically evaluated.
Aya Yamamoto, Yuki Enomoto, Mai Sakurai, Oki Watanabe, Yoshifumi Kanayama, Yumi Koike, Takashi Sakaida, Akimichi Morita   +7 more
wiley   +1 more source

Agonistic autoantibodies targeting AT1R and ETAR: Mechanistic insights and emerging implications in cardiovascular disease. [PDF]

J Transl Autoimmun
Tona F, Bernava G, Civieri G.
europepmc   +1 more source

Ca2+‐Activated Cl− Channels: Do Bestrophins and TMEM16A Interact?

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim Ca2+‐activated Cl– conductances are present in many cell types and are important for regulating membrane potential as well as other cellular functions. TMEM16A is widely accepted as the principal molecular basis for Ca2+‐activated Cl– conductances, but also members of the bestrophin family may be important for some Ca2+‐activated Cl ...
Christian Aalkjær, Vibeke Secher Dam, Holger Nilsson, Donna B. Boedtkjer, Vladimir Matchkov   +4 more
wiley   +1 more source

In silico prioritisation of EDN1 missense variants identifies mature endothelin-1 substitutions with predicted receptor-binding effects. [PDF]

BMC Genomics
Sivakumar R, Arul Senghor KA, Vinodhini VM, Ramkumar KM.   +3 more
europepmc   +1 more source

Heparanase inhibition prevents glycocalyx damage and albuminuria in experimental minimal change disease

Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.
Michael Crompton, Raina D. Ramnath, Kai Betteridge, Sara Desideri, Aldara Martin Alonso, Lulu Jiang, Monica Gamez, Holly Stowell‐Connolly, Viktoriia Vasylchenko, Karen L. Onions, Matthew J. Butler, Chris R. Neal, Andrew H. J. Salmon, Jeremy E. Turnbull, Hiroshi Kawachi, Olga V. Zubkova, Gavin I. Welsh, Simon C. Satchell, Rebecca R. Foster   +18 more
wiley   +1 more source