Results 41 to 50 of about 812 (122)
Lipids in Health and Disease, 2020 Background Quercetin was reported to be crucial for a broad range of activities, including attenuating inflammation, platelet aggregation, capillary permeability, and lipid peroxidation.
Xia Sun, Shuping Zhang, Haitao Song
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Endothelin-1 Role in Human Eye: A Review
Journal of Ophthalmology, 2010 Endothelin is a potent vasoactive peptide occurring in three isotypes, ET-1, ET-2, and ET-3. Through its two main receptors, endothelin A and endothelin B, it is responsible for a variety of physiological functions, primarily blood flow control.
Serena Salvatore, Enzo Maria Vingolo
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Ufl1 deficiency causes skin pigmentation by up-regulation of Endothelin-1
Frontiers in Cell and Developmental Biology, 2022 Ufmylation (UFM1 modification) is a newly identified ubiquitin-like modification system involved in numerous cellular processes. However, the regulatory mechanisms and biological functions of this modification remain mostly unknown.
Ke Wang +8 more
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YAP and endothelin-1 signaling: an emerging alliance in cancer
Journal of Experimental & Clinical Cancer Research, 2021 The rational making the G protein-coupled receptors (GPCR) the centerpiece of targeted therapies is fueled by the awareness that GPCR-initiated signaling acts as pivotal driver of the early stages of progression in a broad landscape of human malignancies.
Piera Tocci +2 more
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Endothelin-1 Serum Concentration in Pediatric Chronic Idiopathic Uveitis
Clinical Ophthalmology, 2021 Katarzyna Powierza,1 Jolanta Sawicka-Powierza,2 Beata Urban,3 Beata Żelazowska-Rutkowska,4 Bogdan Cylwik,4 Bożena Mikołuć,5 Olga Kowalewska,6 Alina Bakunowicz-Łazarczyk3 1University Clinical Hospital in Bialystok, Medical University of Bialystok ...
Powierza K +7 more
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Endothelium-derived endothelin-1 mediates sickle cell nephropathy
FunctionSickle cell nephropathy (SCN) significantly shortens the life expectancy of patients with sickle cell disease (SCD). We previously reported that endothelin-1 (ET-1) and endothelin A receptor (ETA) are upregulated in SCN, and ETA antagonism mitigates SCN ...
Malgorzata Kasztan +6 more
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Endothelin-1 contributes to the development of virus-induced demyelinating disease
Journal of Neuroinflammation, 2020 Background Experimental autoimmune encephalitis (EAE) and virally induced demyelinating disease are two major experimental model systems used to study human multiple sclerosis.
Young-Hee Jin +4 more
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Evaluation of Urinary Big Endothelin-1 in Feline Spontaneous CKD
Animals, 2020 The endothelin-1 (ET-1) system has been implicated in the development and progression of chronic kidney disease (CKD). No information on big ET-1 in feline urine is available. The purpose of this study was to evaluate if urinary big endothelin-1 (bigET-1)
Marco Giraldi +3 more
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Bladder Endothelin-1 Receptor Binding of Bosentan and Ambrisentan
Journal of Pharmacological Sciences, 2014 .: The present study aimed to characterize bladder endothelin-1 (ET-1) receptor binding of clinically used ET-1 receptor antagonists by using [125I]ET-1.
Ayaka Osano +7 more
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Prognosis of Colorectal Cancer Patients with Elevated Endothelin-1 Concentrations
Asian Journal of Surgery, 2004 Prognostic indicators from clinical, laboratory and pathological data of patients with colorectal cancer are essential to identify high-risk groups in whom adjuvant therapy could be beneficial.
Maqsood M. Elahi, Noel W. Everson
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