Attenuation of ischemic liver injury by a non-selective endothelin receptor antagonist [PDF]
Ishizaki, N +8 more
core +1 more source
Contrasting Actions of Endothelin ETAand ETBReceptors in Cardiovascular Disease
Markus P. Schneider +2 more
openalex +1 more source
Fasting as Medicine: Mitochondrial and Endothelial Rejuvenation in Vascular Aging
Aging impairs cerebrovascular health by driving mitochondrial dysfunction, oxidative stress, endothelial failure, and neurovascular uncoupling, leading to BBB breakdown and cognitive decline. In contrast, time‐restricted feeding/eating counteracts these mechanisms by restoring mitochondrial function, activating adaptive nutrient‐sensing pathways ...
Madison Milan +13 more
wiley +1 more source
Phase 2 study of combination SPI-1620 with docetaxel as second-line advanced biliary tract cancer treatment [PDF]
A Rai +30 more
core +3 more sources
No significant differences were observed at any stage of the RCVS course between patients and controls. Systemic arterial stiffness, as assessed by PWV, remained normal and stable throughout the course of RCVS. No systemic complication has been detected during the RCVS course.
Pacôme Constant dit Beaufils +7 more
wiley +1 more source
Ultraviolet B irradiation increases endothelin‐1 and endothelin receptor expression in cultured human keratinocytes [PDF]
Ryoji Tsuboi +6 more
openalex +1 more source
Environmental modulators of vascular physiology and inflammation
Abstract Environmental factors play a crucial role in modulating vascular inflammation, contributing significantly to the development of atherosclerosis and cardiovascular disease. This review synthesizes current evidence on how various environmental exposures influence vascular function and inflammation, with a focus on pollutants such as particulate ...
Anusha N. Seneviratne +3 more
wiley +1 more source
Neuroprotective Effect of IRL-1620, an Endothelin B Receptor Agonist, on a Pediatric Rat Model of Middle Cerebral Artery Occlusion. [PDF]
Cifuentes EG +4 more
europepmc +1 more source
Reduced Expression of the Endothelin Receptor Type B Gene in Piebald Mice Caused by Insertion of a Retroposon-like Element in Intron 1 [PDF]
Takahisa Yamada +5 more
openalex +1 more source
Pathogenic Gαo Mutants Drive Dominant GPCR Coupling in GNAO1 Encephalopathies
Mutations in GNAO1, the gene encoding Gαo, are associated with a wide range of neurodevelopmental disorders. In this study, we show that Gαo variants linked to the most severe patient phenotypes fail to disengage from activated Gi/o‐coupled GPCRs, thereby blocking GRK‐mediated receptor phosphorylation and internalization.
Yonika A. Larasati +4 more
wiley +1 more source

