Results 151 to 160 of about 2,437,403 (392)

Environmental modulators of vascular physiology and inflammation

open access: yesExperimental Physiology, EarlyView.
Abstract Environmental factors play a crucial role in modulating vascular inflammation, contributing significantly to the development of atherosclerosis and cardiovascular disease. This review synthesizes current evidence on how various environmental exposures influence vascular function and inflammation, with a focus on pollutants such as particulate ...
Anusha N. Seneviratne   +3 more
wiley   +1 more source

Safety and tolerability of bosentan in the management of pulmonary arterial hypertension

open access: yesDrug Design, Development and Therapy, 2009
Kari E Roberts, Ioana R PrestonPulmonary, Critical Care and Sleep Medicine, Tufts Medical Center, Boston, Massachusetts, USAAbstract: Endothelin receptor antagonism has emerged as an important therapeutic approach in pulmonary arterial hypertension (PAH).
Kari E Roberts, Ioana R Preston
doaj  

HERVs, transposons and human diseases : part 3 [PDF]

open access: yes, 2012
Part 1 and 2 of this article can be found through theses links: https://www.um.edu.mt/library/oar//handle/123456789/12961 https://www.um.edu.mt/library/oar//handle/123456789/13012Part 3 of the article.
Baldacchino, Sandra, Grech, Alfred
core   +1 more source

Establishment of a mouse model for ischaemic heart failure induced by coronary microembolization via left ventricular oil injection

open access: yesExperimental Physiology, EarlyView.
Abstract Over the past three decades, there has been a steady increase in clinical attention to ischaemic heart failure caused by coronary microembolization. Nonetheless, a suitable mouse model for studying this condition remains limited. In the present study, we developed a mouse model of coronary microembolization‐induced ischaemic heart failure by ...
Lang Pei   +10 more
wiley   +1 more source

Endothelin receptor B, a candidate gene from human studies at high altitude, improves cardiac tolerance to hypoxia in genetically engineered heterozygote mice [PDF]

open access: bronze, 2015
Tsering Stobdan   +10 more
openalex   +1 more source

Human adaptation to high‐altitude: A contemporary comparison of the oxygen cascade in Andean, Tibetan and Ethiopian highlanders

open access: yesExperimental Physiology, EarlyView.
Abstract Human populations native to high altitude have evolved distinct physiological adaptations to chronic hypoxia. This adaptation is evident in the O2 transport cascade. In this review, with brief inclusion of the related genetic adaptations, we compare the O2 cascade across three well‐characterized high‐altitude populations: Andeans (Aymara and ...
Ayechew A. Getu   +5 more
wiley   +1 more source

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