Results 161 to 170 of about 2,334,067 (354)

Safety, efficacy, and clinical utility of macitentan in the treatment of pulmonary arterial hypertension

open access: yesDrug Design, Development and Therapy, 2016
Thomas J Monaco,1 Carlos D Davila2 1Division of Pulmonary and Critical Care Medicine, Baylor College of Medicine, Houston, TX, 2Department of Medicine, Einstein Medical Center, Philadelphia, PA, USA Abstract: Pulmonary arterial hypertension is a ...
Monaco TJ, Davila CD
doaj  

Pathology Seen in Myenteric Plexus in Two Subjects With Waardenburg Syndrome

open access: yesNeurogastroenterology &Motility, EarlyView.
Ganglion cells immunohistochemically labeled with pan‐neuronal marker HuC/D in sections from ileum. Note the different number of stained cells in the myenteric plexus. A, control subject, B, patient with SOX10 mutation (hypoganglionosis) C, patient with EDN3 mutation (aganlionosis). Both patients diagnosed with Waardenburg syndrome type 4 including gut
Björn Ersson   +3 more
wiley   +1 more source

Inspiratory Muscle Training on Exercise Capacity, Dyspnoea and Health Status in Pulmonary Hypertension: A Randomised Controlled Trial

open access: yesRespirology, EarlyView.
ABSTRACT Background and Objective To evaluate the effects of a high‐intensity inspiratory muscle training on respiratory muscle strength, exercise capacity, dyspnoea, and health‐related quality of life (HRQL) in patients with pulmonary hypertension (PH). Methods Single‐blinded, randomised controlled trial 35 women with clinically stable PH (subgroups 1
Fabrício Farias da Fontoura   +8 more
wiley   +1 more source

Functional Role of Na+/H+ Exchanger in Ca2+ Influx Mediated via Human Endothelin Type A Receptor Stably Expressed in Chinese Hamster Ovary Cells

open access: yesJournal of Pharmacological Sciences, 2008
This study examines the functional role of Na+/H+ exchanger (NHE) in Ca2+ influx mediated by human endothelin type A receptor (ETAR) expressed in Chinese hamster ovary (CHO) cells.
Takahiro Horinouchi   +6 more
doaj  

Updated insights into the molecular pathogenesis of canine atopic dermatitis

open access: yesVeterinary Dermatology, EarlyView.
Abstract Atopic dermatitis (AD) is a common and chronic inflammatory skin disease with frequent relapses. The genomics revolution has greatly contributed and revolutionised our knowledge of human AD; understanding the molecular skin fingerprint of AD and associated pathogenic immune pathways has led to preclinical assessments of several novel ...
Frane Banovic
wiley   +1 more source

Angiotensin and Endothelin Receptor Structures With Implications for Signaling Regulation and Pharmacological Targeting. [PDF]

open access: yesFront Endocrinol (Lausanne), 2022
Speck D   +6 more
europepmc   +1 more source

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