Results 221 to 230 of about 2,334,067 (354)

Gαq signalling from endosomes: A new conundrum

British Journal of Pharmacology, Volume 182, Issue 14, Page 3068-3089, July 2025.
Abstract G‐protein‐coupled receptors (GPCRs) constitute the largest family of membrane receptors, and are involved in the transmission of a variety of extracellular stimuli such as hormones, neurotransmitters, light and odorants into intracellular responses.
Carole Daly, Bianca Plouffe
wiley   +1 more source

Maximizing the Therapeutic Effect of Endothelin Receptor Antagonists in Pulmonary Fibrosis: A Paradigm for Treating the Disease. [PDF]

Int J Mol Sci
Cantor J.
europepmc   +1 more source

Gender differences in genotypic distribution of endothelin-1 gene and endothelin receptor A gene in pulmonary hypertension associated with rheumatic mitral valve disease. [PDF]

Indian Heart J, 2022
Mehra P, Mehta V, Yusuf J, Mukhopadhyay S, Dabla PK, Parashar L, Sukhija R, Aronow WS.   +7 more
europepmc   +1 more source

LU 302 872 and Its Racemate (LU 224 332) Show Balanced Endothelin-A/B Receptor Affinity, High Oral Activity, and Inhibit Human Prostate Tissue Contractions

, 1998
Manfred Raschack, Silvia Göck, Liliane Unger, Alfred Hahn, Willi M. Amberg, Roef Jansen, P. Alken, Alwin Weber, Stefan Hergenröder   +8 more
openalex   +1 more source

Essential role for endothelin ET_B receptors in fever induced by LPS (E. coli) in rats [PDF]

, 1998
Aline S.C. Fabricio, Carlos A A Silva, Giles A. Rae, Pedro D’Orléans-Juste, Glória Emília Petto de Souza   +4 more
openalex   +1 more source

The dark sides of the GPCR tree ‐ research progress on understudied GPCRs

British Journal of Pharmacology, Volume 182, Issue 14, Page 3109-3134, July 2025.
Abstract A large portion of the human GPCRome is still in the dark and understudied, consisting even of entire subfamilies of GPCRs such as odorant receptors, class A and C orphans, adhesion GPCRs, Frizzleds and taste receptors. However, it is undeniable that these GPCRs bring an untapped therapeutic potential that should be explored further.
Magdalena M. Scharf, Laura J. Humphrys, Sandra Berndt, Antonella Di Pizio, Juliane Lehmann, Ines Liebscher, Alessandro Nicoli, Masha Y. Niv, Lior Peri, Hannes Schihada, Gunnar Schulte   +10 more
wiley   +1 more source

Endothelin receptor antagonism improves glucose tolerance and adipose tissue inflammation in an experimental model of systemic lupus erythematosus.

Am J Physiol Endocrinol Metab, 2023
Rivera-Gonzalez O, Case CT, Wilson NA, Speed JS, Taylor EB.   +4 more
europepmc   +1 more source

Efficacy and safety of endothelin receptor antagonists, phosphodiesterase type 5 Inhibitors, and prostaglandins in pediatric pulmonary arterial hypertension: A network meta-analysis. [PDF]

Front Cardiovasc Med, 2022
Cao F, Wu K, Zhu YZ, Jiang JJ, Zhang G, Liu J, Xiao P, Tian Y, Zhang W, Zhang S, Hou F, Bao ZW.   +11 more
europepmc   +1 more source

Localization of endothelin receptors in rat renal medulla.

, 1996
Tokihito Yukimura, Mitsuru Notoya, Kenji MIZOJIRI, Takeshi Matsuura, Tsuneyuki Ebara, Katsuyuki Miura, Shokei Kim, Hiroshi Iwao   +7 more
openalex   +1 more source

Ca²⁺ signalling by endothelin receptors in rat and human cultured airway smooth muscle cells [PDF]

, 1998
Michael J. Maxwell, R.G. Goldie, Peter J. Henry   +2 more
openalex   +1 more source