Results 261 to 270 of about 2,334,067 (354)

Isoliquiritigenin Promotes the Repair of High Uric Acid‐Induced Vascular Injuries

Smart Medicine, Volume 4, Issue 2, June 2025.
High uric acid‐induced vascular injuries are always accompanied with hyperuricemia, for which seeking for effective safety drugs is an urgent and crucial problem that needs to be solved. Here, we have successfully screened isoliquiritigenin out from multiplex traditional Chinese medicine monomers in promoting the repair of high uric acid‐induced ...
Hongyan Zhou, Xinyu Song, Yingying Tian, Lili Zhao, Jingyi Yang, Fangfu Ye, Ting Cao, Jiayu Zhang   +7 more
wiley   +1 more source

Aldosterone Inactivates the Endothelin-B Receptor via a Cysteinyl Thiol Redox Switch to Decrease Pulmonary Endothelial Nitric Oxide Levels and Modulate Pulmonary Arterial Hypertension

Circulation, 2012
B. Maron, Ying‐yi Zhang, Kevin P. White, S. Y. Chan, D. Handy, Christopher E. Mahoney, J. Loscalzo, J. Leopold   +7 more
semanticscholar   +1 more source

Biotransformation of Ambrisentan by A. niger and P. mineoluteum Monitored by High Performance Liquid Chromatography and Ultra High Performance Liquid Chromatography/Quadrupole Time‐of‐Flight Mass Spectrometry

SEPARATION SCIENCE PLUS, Volume 8, Issue 6, June 2025.
ABSTRACT The focus of the present study was the monitoring of ambrisentan (AMB) in vitro biotransformation by two fungal cultures: Aspegillus niger ATCC 9029 and Penicillium mineoluteum URM 6889. This drug is a selective endothelin Type A, receptor antagonist, used for pulmonary arterial hypertension.
Rafaela Martins Sponchiado, Brendha Lang Camboim, Julia Medeiros Sorrentino, Leticia Cordenonsi, Alexsandro Dallegrave, Alexandre Meneghello Fuentefria, Martin Steppe, Cássia Virginia Garcia   +7 more
wiley   +1 more source

Chronic Effects of a Novel, Orally Active Endothelin Receptor Antagonist, T-0201, in Dogs with Congestive Heart Failure

, 1998
Masato Ohnishi, Atsuyuki Wada, Takayoshi Tsutamoto, Daisuke Fukai, Masahide Sawaki, Yukiharu Maeda, Masahiko Kinoshita   +6 more
openalex   +1 more source

Primary right ventricular cardiac haemangiosarcoma with pulmonary metastases in a domestic short‐haired cat

Veterinary Record Case Reports, Volume 13, Issue 2, June 2025.
Abstract A 5‐year‐old, male, neutered, domestic short‐haired cat presented for lethargy and anorexia and was diagnosed with a cardiac tumour and likely pulmonary metastases by ultrasonography and contrast computed tomography of the thorax. Clinically, the cat presented with right‐sided heart failure, pleural and pericardial effusion and ensuing ...
Samuel Kalpers, George Smith, Angie Rupp
wiley   +1 more source

Polyphenols for the Prevention or Management of Preeclampsia: A Systematic Review and Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 132, Issue 7, Page 867-879, June 2025.
ABSTRACT Objectives To evaluate the effects of polyphenol‐containing products during pregnancy on preeclampsia‐related maternal and neonatal outcomes. Design Systematic review and meta‐analysis. Setting Nine databases and one trial registry, from inception to August 11th, 2023.
Phi‐Yen Nguyen, Ben Sanderson, Maureen Makama, Kate Mills, Anne Ammerdorffer, A. Metin Gülmezoglu, Joshua P. Vogel, Annie R. A. McDougall   +7 more
wiley   +1 more source

Cigarette smoke exposure up‐regulates endothelin receptor B in human pulmonary artery endothelial cells: molecular and functional consequences

British Journal of Pharmacology, 2010
J. Milara, J. Ortiz, G. Juan, Ricardo Guijarro, P. Almudéver, Miguel Martorell, E. Morcillo, Julio Cortijo   +7 more
semanticscholar   +1 more source

Rare but relevant: The injection of tablet preparations and pulmonary hypertension

Addiction, Volume 120, Issue 6, Page 1276-1279, June 2025.
Abstract Intravascular injection of dissolved medicinal preparations such as crushed tablets is associated with a risk of injecting particulate material into the vasculature. This particulate material will naturally pass to the lungs where it will be largely filtered out in the pulmonary vascular bed, and in turn, it can result in a range of ...
Johan Duflou
wiley   +1 more source

Endothelin receptor blockade blunts the pressor response to acute stress in men and women with obesity.

J Appl Physiol (1985), 2022
Derella CC, Blanks AM, Wang X, Tucker MA, Horsager C, Jeong JH, Rodriguez-Miguelez P, Looney J, Thomas J, Pollock DM, Harris RA.   +10 more
europepmc   +1 more source

SorCS2 Is Important for Astrocytic Function in Neurovascular Signaling

Acta Physiologica, Volume 241, Issue 6, June 2025.
ABSTRACT Introduction The receptor SorCS2 is involved in the trafficking of membrane receptors and transporters. It has been implicated in brain disorders and has previously been reported to be indispensable for ionotropic glutamatergic neurotransmission in the hippocampus.
Christian Staehr, Hande Login, Elizaveta V. Melnikova, Magdalena Bakun, Ewelina Ziemlinska, Lilian Kisiswa, Simin Berenji Ardestani, Stella Solveig Nolte, Hans Christian Beck, Line Mathilde Brostrup Hansen, Dmitry Postnov, Alexei Verkhratsky, Anna R. Malik, Anders Nykjaer, Vladimir V. Matchkov   +14 more
wiley   +1 more source