Results 271 to 280 of about 2,437,403 (392)

Knowledge Gaps and Controversies on Cardiopulmonary Exercise Testing in the Assessment of Pulmonary Vascular Disease: An Official Statement of the Pulmonary Vascular Research Institute Exercise and Right Ventricular Function Task Force

Pulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Exercise testing has long been essential for evaluating diagnosis, prognosis, and functional status in pulmonary hypertension (PH). Recent advances have clarified its role in defining reference values and prognostic markers. Nonetheless, substantial knowledge gaps persist regarding the implementation of invasive cardiopulmonary exercise ...
Aaron B. Waxman, Abraham Babu, Roberto Badagliacca, Eloara Ferreira, Patty George, Marco Guazzi, Luke Howard, Darlene Kim, Gabor Kovacs, Saad Kubba, David Langleben, Colm McCabe, Thais Menezes, Rudolf Oliveira, Stylianos Orfanos, Inderjit Singh, David Systrom, Ryan Tedford, Rebecca Vanderpool, Carmine Dario Vizza, Franz P. Rischard   +20 more
wiley   +1 more source

Targeting the activated allosteric conformation of the endothelin receptor B in melanoma with an antibody-drug conjugate: mechanisms and therapeutic efficacy. [PDF]

BJC Rep
Herbet A, Hautière M, Jean-Alphonse F, Vivier D, Leboeuf C, Costa N, Mabondzo A, Bousquet G, Denat F, Reiter E, Boquet D.   +10 more
europepmc   +1 more source

Subcutaneous Treprostinil in PH Associated With Left Heart Disease or Chronic Lung Disease

Pulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Pulmonary hypertension (PH) associated with left heart disease (LHD‐PH) and pulmonary hypertension associated with chronic lung disease (CLD‐PH) are the most common PH subtypes but lack effective treatments. In a prospective cohort study, 90 patients (39 LHD‐PH, 51 CLD‐PH) with severe disease [pulmonary vascular resistance (PVR) > 5 Wood units
Roela Sadushi‐Koliçi, Leila Alajbegovic, Vladimir Gojic, Nika Skoro‐Sajer, Ioana Campean, Inbal Shafran, Deddo Mörtl, Christian Gerges, Irene M. Lang   +8 more
wiley   +1 more source

Recent developments in the management of resistant hypertension: focus on endothelin receptor antagonists. [PDF]

Future Cardiol
Heidari Nejad S, Azzam O, Schlaich MP.
europepmc   +1 more source

Methamphetamine‐Associated Pulmonary Arterial Hypertension: Impact, Mechanisms, and a Framework for Management

Pulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Methamphetamine‐associated pulmonary arterial hypertension (Meth‐PAH) is an increasingly prevalent but understudied subtype of Group 1 pulmonary arterial hypertension (PAH). While most prevalent in the Western United States, its reach continues to expand with the evolving global methamphetamine epidemic.
Namita Sood, Jonika Weerasekare, Iryna Zhyvylo, Elena A. Goncharova, Teresa De Marco   +4 more
wiley   +1 more source

Vascular endothelin receptor type B: structure, function and dysregulation in vascular disease.

Biochemical Pharmacology, 2012
M. Mazzuca, R. Khalil
semanticscholar   +1 more source

Isolated Anti‐SS‐A Antibody Seropositivity as a Poor Prognostic Factor in Systemic Sclerosis: Insights From a Cohort of 307 Cases

The Journal of Dermatology, Volume 53, Issue 1, Page 41-53, January 2026.
ABSTRACT Systemic sclerosis is an autoimmune disease characterized by vasculopathy, fibrosis, and immune dysregulation. Anti‐SS‐A antibodies (anti‐SSA) have been reported to confer severe clinical manifestations in some Western and Japanese cohorts. We aimed to determine whether anti‐SSA seropositivity affects clinical outcomes in Japanese patients. We
Nana Ishida, Kazuki M. Matsuda, Hirohito Kotani, Hayakazu Sumida, Shinichi Sato   +4 more
wiley   +1 more source

Blockade of endothelin receptors mitigates SARS-CoV-2-induced osteoarthritis

Man Ting Au, Junguo Ni, Kaiming Tang, Wei Wang, Lanlan Zhang, Hantang Wang, Fangyi Zhao, Zhan Li, Peng Luo, Lawrence Chun‐Man Lau, PK Chan, Cuiting Luo, Bo Zhou, Lin Zhu, Charlie Yuli Zhang, Tianshu Jiang, Marianne Lauwers, Jasper Fuk‐Woo Chan, Shuofeng Yuan, Chunyi Wen   +19 more
openalex   +2 more sources

Endothelin-1 (ET-1) and its receptors on haemorrhoidal tissue: A potential site for therapeutic intervention

, 2013
Michael R. Dashwood, Varut Lohsiriwat, V.G. Wilson, J H Scholefield   +3 more
openalex   +1 more source

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

British Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 58-72, January 2026.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post, Cayla Denney, Adam Cohen, Jens Jordan, Ulrich Limper   +4 more
wiley   +1 more source