Results 281 to 290 of about 2,437,403 (392)

Addressing unmet needs for chronic kidney disease treatment in type 1 diabetes: A review

Diabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 16-26, January 2026.
Abstract Chronic kidney disease (CKD) is a serious complication occurring in nearly one of three people with type 1 diabetes (T1D). Major therapeutic advances have been made in the management of CKD for people with type 2 diabetes (T2D), thereby improving their kidney, cardiovascular, and survival outcomes.
Katherine R. Tuttle, Linong Ji, Chantal Mathieu, Jonathan Rosen   +3 more
wiley   +1 more source

Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk

Proceedings of the National Academy of Sciences of the United States of America, 2011
Katsuhito Yasuno, Mehmet Bakırcıoğlu, Siew-Kee Low, Kaya Bilgüvar, E. Gaál, Y. Ruigrok, M. Niemelä, A. Hata, P. Bijlenga, H. Kasuya, J. Jääskeläinen, D. Krex, G. Auburger, M. Simon, B. Krischek, A. Ozturk, S. Mane, G. Rinkel, H. Steinmetz, J. Hernesniemi, K. Schaller, H. Zembutsu, I. Inoue, A. Palotie, F. Cambien, Yusuke Nakamura, R. Lifton, Murat Günel   +27 more
semanticscholar   +1 more source

Endothelin receptor antagonists (ERAs) can potentially be used as therapeutic drugs to reduce hypertension caused by small molecule tyrosine kinase inhibitors (TKIs). [PDF]

Front Pharmacol
He Q, Lin J, Mo C, Li G, Lu J, Sun Q, Cao L, Gan H, Sun Q, Yao J, Lian S, Wang W.   +11 more
europepmc   +1 more source

Endothelin receptor A-specific stimulation of glomerular inflammation and injury in a streptozotocin-induced rat model of diabetes

Diabetologia, 2011
Mohamed A. Saleh, Erika I Boesen, Jennifer S. Pollock, V. Savin, David M. Pollock   +4 more
semanticscholar   +1 more source

Endothelin Receptor Antagonists for Kidney Protection: Lessons from the SONAR Trial.

Clin J Am Soc Nephrol, 2022
Heerspink HJL, de Zeeuw D.
europepmc   +1 more source

Cardiovascular biomarkers and preeclampsia: A narrative review

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Preeclampsia (PE) is a complex pregnancy disorder linked to cardiovascular disease (CVD) through shared risk factors and epidemiological associations. Cardiovascular biomarkers are valuable for predicting, diagnosing and assessing PE, as well as estimating future CVD risk. This review explores current cardiovascular biomarkers used in clinical practice
Johana Ullmo, Madalina Nicoleta Nan, Mónica Cruz‐Lemini, Carmen Garrido‐Gimenez, Judit Platero, Álvaro García‐Osuna, Pablo García‐Manau, Marcel Twickler, Elisa Llurba   +8 more
wiley   +1 more source

A matter arising: When should inflammatory and autoimmune rheumatic diseases be considered ‘early’?

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Timely recognition of inflammatory and autoimmune rheumatic diseases (IARDs) is important to optimize the early diagnosis with tailored interventions and possible prevention of irreversible organ damage. This narrative review provides an update by summarizing the advances in identifying the early stages of rheumatoid arthritis, systemic sclerosis and ...
Elvis Hysa, Emanuele Gotelli, Carmen Pizzorni, Sabrina Paolino, Alberto Sulli, Vanessa Smith, Rosanna Campitiello, Maurizio Cutolo   +7 more
wiley   +1 more source

The effect of the endothelin receptor antagonist atrasentan on insulin resistance in phenotypic clusters of patients with type 2 diabetes and chronic kidney disease. [PDF]

Diabetes Obes Metab
Smeijer JD, Gomez MF, Rossing P, Heerspink HJL.   +3 more
europepmc   +1 more source

Endothelin receptor subtypes und their function in the human urinary bladder smooth muscle

, 1995
Takako Koizumi, Masayuki Takeda, Kenji Obara, Takeshi Komeyama   +3 more
openalex   +1 more source

Integrated Network Pharmacology, Single‐Cell Transcriptomics Unveil the Mechanistic Role of Morusin in Aortic Dissection

Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT Aortic dissection is a life‐threatening cardiovascular emergency with limited pharmacological options. This study focuses on elucidating the multi‐target and multi‐pathway mechanisms through which morusin mitigates aortic dissection progression, integrating network pharmacology, single‐cell transcriptomics and experimental validation.
Zhaomeng Wang, Haoran Zhang, Zhanxiong Xie, Yukun Xiang, Yiwen Fu, Zixun Wang, Haiqing Jiao, Nan Lin, Chenguang Niu, Chao Jiang, Lemin Zheng   +10 more
wiley   +1 more source