Results 311 to 320 of about 2,437,403 (392)

The Use of Tranexamic Acid to Treat Melasma: A Systematic Review and Meta‐Analysis

open access: yesDermatologic Therapy, Volume 2026, Issue 1, 2026.
Introduction Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine that inhibits bleeding due to its effects on plasminogen conversion, approved by the FDA to treat menorrhagia and prevent bleeding in hemophilia patients undergoing dental extraction.
Nabila Scabine Pessotti   +7 more
wiley   +1 more source

A Review of Emerging Biomarkers Connecting Diabetes and Ischemic Stroke: Implications for Early Detection and Risk Stratification

open access: yesJournal of Diabetes Research, Volume 2026, Issue 1, 2026.
Diabetes substantially increases the risk of ischemic stroke through complex metabolic, inflammatory, and vascular mechanisms, yet early identification of high‐risk individuals remains challenging. This narrative review synthesizes emerging circulating and genomic biomarkers that illuminate the pathways linking diabetes and ischemic stroke and ...
Nadia Hussain   +4 more
wiley   +1 more source

Intracavernous Injection of Mechanically Extracted Stromal Vascular Fragments Suppresses Endothelial‐Mesenchymal Transformation to Mitigate Erectile Dysfunction in Hypertensive Rats

open access: yesStem Cells International, Volume 2026, Issue 1, 2026.
Erectile dysfunction (ED) is widespread among individuals with high blood pressure and negatively affects quality of life. The effect of stromal vascular fraction (SVF) on hypertension‐related ED remains unexplored. We used a hypertensive rat model to explore the relative efficacy of adipose tissue stromal vascular fraction (tSVF) and cellular SVF ...
Cheng Shao   +9 more
wiley   +1 more source

Perivascular adipose tissue from female rats fed a high‐fat diet impaired mesenteric artery vasodilation

open access: yesPhysiological Reports, Volume 14, Issue 2, January 2026.
Abstract High‐fat diet (HFD) is a cardiovascular risk factor that may disproportionately affect women compared to men. HFD alters perivascular adipose tissue (PVAT), which surrounds arteries and regulates vascular function. This study investigated the sex‐specific effects of HFD on PVAT‐mediated vascular dysfunction. Male and female Sprague‐Dawley rats
Gurneet S. Sangha   +6 more
wiley   +1 more source

Effects of arginine vasopressin deficiency on cardiac fibrosis in male Wistar rats

open access: yesPhysiological Reports, Volume 14, Issue 2, January 2026.
Abstract Cardiac fibrosis represents a consequence of hypertensive heart disease and is associated with ventricular dysfunction, arrhythmias, and mortality. Arginine vasopressin (AVP) promotes myofibroblast proliferation and collagen synthesis through V1a receptors.
A. Limón‐Mendoza   +7 more
wiley   +1 more source

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