Results 71 to 80 of about 2,334,067 (354)
Aprocitentan: A new development of resistant hypertension
The Journal of Clinical Hypertension, 2023 As the blood pressure threshold for commencing antihypertensive treatment diminishes, the cohort suffering from resistant hypertension (RH) correspondingly expands.
Yao Yao +4 more
doaj +1 more source
Cancer Communications, EarlyView.Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu +12 more
wiley +1 more source
پزشکی بالینی ابن سینا, 2021 Background and Objective: Due to the significant importance of the teeth in mastication, speech, and aesthetics, it is necessary to identify all involved genes in the tooth development. Therefore, this study aimed to evaluate the role of endothelin-1 and
Soussan Irani +2 more
doaj
Epigenetic Changes Related to Hypertension in Asian Adults: A Systematic Review
Chronic Diseases and Translational Medicine, EarlyView.PRISMA study flow diagram. ABSTRACT Background Elevated high blood pressure is controlled by complicated, little‐understood genetic and epigenetic pathways that are influenced by both heritable and environmental variables. Many adult systolic and diastolic blood pressure‐related genomic loci have been identified through previous genome‐wide association
Lilik Sukesi +7 more
wiley +1 more source
Endothelin increases the proliferation of rat olfactory mucosa cells
Neural Regeneration Research, 2020 The olfactory mucosa holds olfactory sensory neurons directly in contact with an aggressive environment. In order to maintain its integrity, it is one of the few neural zones which are continuously renewed during the whole animal life.
Bertrand Bryche +5 more
doaj +1 more source
Roles for endothelin receptor B and BCL2A1 in spontaneous CNS metastasis of melanoma.
Cancer Research, 2012 Metastatic spread of melanoma to the central nervous system (CNS) is a common and devastating manifestation of disease progression, which, despite its clinical importance, remains poorly understood with respect to underlying molecular mechanisms. Using a
W. Cruz-Muñoz +11 more
semanticscholar +1 more source
Assessing candidate DLX‐regulated genes in the first pharyngeal arch of chick embryos
Developmental Dynamics, EarlyView.Abstract Background Insights into the development and evolution of asymmetrical jaws will require an understanding of the gene regulatory networks that underpin the differential morphogenesis of the maxillary and mandibular domains of the first pharyngeal arch in a variety of gnathostomes.
Afshan Sohail +2 more
wiley +1 more source
A review of sitaxsentan sodium in patients with pulmonary arterial hypertension
Vascular Health and Risk Management, 2007 Aaron B WaxmanDepartment of Internal Medicine, Pulmonary Critical Care Unit, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USAAbstract: Pulmonary arterial hypertension (PAH) is a life threatening, progressive condition which ...
Aaron B Waxman
doaj
Artery Research, 2009 Background. Experimental cerebral ischemia and organ culture of cerebral arteries result in enhanced expression of endothelin ETB receptors in smooth muscle cells. The present study was designed to evaluate the involvement of calcium-calmodulin dependent
R. Waldsee +3 more
doaj +1 more source
Endothelin receptor A antagonism attenuates renal medullary blood flow impairment in endotoxemic pigs. [PDF]
PLoS ONE, 2011 BACKGROUND: Endothelin-1 is a potent endogenous vasoconstrictor that contributes to renal microcirculatory impairment during endotoxemia and sepsis. Here we investigated if the renal circulatory and metabolic effects of endothelin during endotoxemia are ...
Johan Fenhammar +6 more
doaj +1 more source