ABSTRACT Pulmonary Langerhans cell histiocytosis (PLCH) frequently complicated by pulmonary hypertension (PH), which markedly worsens prognosis. We retrospectively reviewed three institutional PLCH‐PH cases treated with off‐label Sotatercept added to background triple therapy and performed a systematic review of published PLCH‐PH reports (PubMed/Embase
Giorgi Chilingarashvili +7 more
wiley +1 more source
Localization of the therapeutic targets for endothelin receptor antagonists and sodium-glucose co-transporter 2 inhibitors in the chronic liver disease, primary sclerosing cholangitis. [PDF]
Kuc RE +7 more
europepmc +1 more source
Long-Term Administration of Endothelin Receptor Antagonist Improves Coronary Endothelial Function in Patients With Early Atherosclerosis [PDF]
Martin Reriani +9 more
openalex +1 more source
ABSTRACT Exercise testing has long been essential for evaluating diagnosis, prognosis, and functional status in pulmonary hypertension (PH). Recent advances have clarified its role in defining reference values and prognostic markers. Nonetheless, substantial knowledge gaps persist regarding the implementation of invasive cardiopulmonary exercise ...
Aaron B. Waxman +20 more
wiley +1 more source
MP44-13 EFFECTS OF THE RECEPTOR ANTAGONIST PICOTAMIDE ON ENDOTHELIN-1-, -2- AND -3-INDUCED CONTRACTIONS IN HUMAN PROSTATE SMOOTH MUSCLE [PDF]
Alexander Tamalunas +5 more
openalex +1 more source
Subcutaneous Treprostinil in PH Associated With Left Heart Disease or Chronic Lung Disease
ABSTRACT Pulmonary hypertension (PH) associated with left heart disease (LHD‐PH) and pulmonary hypertension associated with chronic lung disease (CLD‐PH) are the most common PH subtypes but lack effective treatments. In a prospective cohort study, 90 patients (39 LHD‐PH, 51 CLD‐PH) with severe disease [pulmonary vascular resistance (PVR) > 5 Wood units
Roela Sadushi‐Koliçi +8 more
wiley +1 more source
Pharmacological Profile in vitro of A New Endothelin Receptor Antagonist, TAK-044.
Yumiko Awane +7 more
openalex +1 more source
SERAPHIN haemodynamic substudy: the effect of the dual endothelin receptor antagonist macitentan on haemodynamic parameters and NT-proBNP levels and their association with disease progression in patients with pulmonary arterial hypertension [PDF]
Nazzareno Galiè +14 more
openalex +1 more source
ABSTRACT Methamphetamine‐associated pulmonary arterial hypertension (Meth‐PAH) is an increasingly prevalent but understudied subtype of Group 1 pulmonary arterial hypertension (PAH). While most prevalent in the Western United States, its reach continues to expand with the evolving global methamphetamine epidemic.
Namita Sood +4 more
wiley +1 more source

