The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets
iNew Medicine, Volume 2, Issue 2, June 2026.The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong +5 more
wiley +1 more source
Maximizing the Therapeutic Effect of Endothelin Receptor Antagonists in Pulmonary Fibrosis: A Paradigm for Treating the Disease. [PDF]
Int J Mol SciCantor J.
europepmc +1 more source
The SONAR study-is there a future for endothelin receptor antagonists in diabetic kidney disease? [PDF]
Ann Transl Med, 2019 Cahn A, Cernea S, Raz I.
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Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
Med Research, Volume 2, Issue 2, Page 309-342, June 2026.The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
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Respirology, Volume 31, Issue 6, Page 621-629, June 2026.Pulmonary arterial baroreceptors reflexively stimulate sympathetic nerve activity (SNA) in response to elevated pulmonary artery pressure and distension. In pulmonary hypertension patients, changes in muscle SNA were proportional to changes in pulmonary haemodynamics following nebulised iloprost.
Michael J. Plunkett +6 more
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Endothelin and endothelin receptor antagonists in systemic rheumatic disease [PDF]
Arthritis & Rheumatism, 2003 openaire +2 more sources
Ca2+‐Activated Cl− Channels: Do Bestrophins and TMEM16A Interact?
Acta Physiologica, Volume 242, Issue 6, June 2026.ABSTRACT Aim Ca2+‐activated Cl– conductances are present in many cell types and are important for regulating membrane potential as well as other cellular functions. TMEM16A is widely accepted as the principal molecular basis for Ca2+‐activated Cl– conductances, but also members of the bestrophin family may be important for some Ca2+‐activated Cl ...
Christian Aalkjær +4 more
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Liver injury due to endothelin receptor antagonists: a real-world study based on post-marketing drug monitoring data. [PDF]
Ther Adv Respir DisDong S, Guo X, Wang H, Sun C.
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Tale of 2 Endothelin Receptor Antagonists in Eisenmenger Syndrome. [PDF]
Circulation, 2019 Ivy D, Wilson N.
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Cardiovascular Health in Women—Across the Lifespan
Clinical Endocrinology, Volume 104, Issue 6, Page 539-555, June 2026.ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar +5 more
wiley +1 more source