Results 171 to 180 of about 285,474 (314)

Recent developments in the management of resistant hypertension: focus on endothelin receptor antagonists. [PDF]

Future Cardiol
Heidari Nejad S, Azzam O, Schlaich MP.
europepmc   +1 more source

Sustained effect of macitentan, a novel oral endothelin receptor antagonist, on exercise capacity and the association of its measure with long-term outcomes in pulmonary arterial hypertension [PDF]

, 2013
Nazzareno Galiè, Richard N. Channick, Marion Delcroix, Hossein Ardeschir Ghofrani, Pavel Jansa, F Brun, G. Simonneau, Lewis J. Rubin   +7 more
openalex   +1 more source

Transmembrane Protein 100 Expression on Endothelial Cells Vascularizing Thrombi in Chronic Thromboembolic Pulmonary Hypertension Modulates TGFβ1−ALK1 Signaling During Angiogenesis

Pulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Endothelial cells within chronic pulmonary artery thrombi in CTEPH overexpress transmembrane protein 100 (TMEM100), an activin A receptor‐like kinase 1 (ACVRL1 or ALK1) signaling‐dependent gene, and TGFβ1 upregulated TMEM100 transcription in healthy lung ECs.
Magdalena L. Bochenek, Iman Ghasemi, Christoph B. Wiedenroth, Olympia Bikou, Ioannis Karampinis, Eric D. Roessner, Lukas Hobohm, Stefan Guth, Philipp Lurz, Stavros Konstantinides, Katrin Schäfer   +10 more
wiley   +1 more source

Selection of Endothelin Receptor Antagonists in the Treatment of Pulmonary Arterial Hypertension: A Comprehensive Narrative Review [PDF]

Naomi Habib, ANKITA ADHIA, David López, Marinella Sandros, P Guichard   +4 more
openalex   +1 more source

Isolated Anti‐SS‐A Antibody Seropositivity as a Poor Prognostic Factor in Systemic Sclerosis: Insights From a Cohort of 307 Cases

The Journal of Dermatology, Volume 53, Issue 1, Page 41-53, January 2026.
ABSTRACT Systemic sclerosis is an autoimmune disease characterized by vasculopathy, fibrosis, and immune dysregulation. Anti‐SS‐A antibodies (anti‐SSA) have been reported to confer severe clinical manifestations in some Western and Japanese cohorts. We aimed to determine whether anti‐SSA seropositivity affects clinical outcomes in Japanese patients. We
Nana Ishida, Kazuki M. Matsuda, Hirohito Kotani, Hayakazu Sumida, Shinichi Sato   +4 more
wiley   +1 more source

Azole Endothelin Antagonists. 1. A Receptor Model Explains an Unusual Structure−Activity Profile

, 1996
Thomas W von Geldern, Charles W. Hutchins, Jeffrey A. Kester, Jinshyun R. Wu‐Wong, William J. Chiou, Douglas B. Dixon, Terry J. Opgenorth   +6 more
openalex   +1 more source

The effects of TBC3214, a selective endothelin ETA receptor antagonist, on orthodontic tooth movement in rats [PDF]

, 2007
Špela Sprogar, J. Volk, Martina Drevenšek, Gorazd Drevenšek   +3 more
openalex   +1 more source

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

British Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 58-72, January 2026.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post, Cayla Denney, Adam Cohen, Jens Jordan, Ulrich Limper   +4 more
wiley   +1 more source

EFFECTS OF COMBINED RIOCIGUAT AND ENDOTHELIN RECEPTOR ANTAGONIST THERAPY IN CHINESE PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION

Anqi Duan, Zhihua Huang, Zhihui Zhao, Qing Zhao, Xin Li, Sicheng Zhang, Luyang Gao, Qin Luo, Zhihong Liu   +8 more
openalex   +1 more source

Pharmacological Properties of J-104132 (L-753,037), a Potent, Orally Active, Mixed ETA/ETB Endothelin Receptor Antagonist

, 1999
M. Nishikibe, Hisashi Ohta, Megumu Okada, Kinji Ishikawa, Takashi Hayama, Takahiro Fukuroda, Kazuhito Noguchi, Michiyasu Saito, Takeshi Kanoh, Satoshi Ozaki, Tomoe Kamei, Kaori Hara, D. William, Salah D. Kivlighn, Stephen M. Krause, Robert A. Gabel, Gloria J. Zingaro, Nancy A. Nolan, John T. O’Brien, Franklin C. Clayton, Joseph J. Lynch, Douglas J. Pettibone, Peter K. S. Siegl   +22 more
openalex   +1 more source