Results 241 to 250 of about 37,353 (347)

Endothelin-A-receptor antagonism with atrasentan exhibits limited activity on the KU-19-19 bladder cancer cell line in a mouse model

, 2009
Edwin Herrmann, Arne Tiemann, Elke Eltze, Christian Bolenz, Christoph Bremer, Thorsten Persigehl, L. Hertle, Christian Wülfing   +7 more
openalex   +2 more sources

Transmembrane Protein 100 Expression on Endothelial Cells Vascularizing Thrombi in Chronic Thromboembolic Pulmonary Hypertension Modulates TGFβ1−ALK1 Signaling During Angiogenesis

Pulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Endothelial cells within chronic pulmonary artery thrombi in CTEPH overexpress transmembrane protein 100 (TMEM100), an activin A receptor‐like kinase 1 (ACVRL1 or ALK1) signaling‐dependent gene, and TGFβ1 upregulated TMEM100 transcription in healthy lung ECs.
Magdalena L. Bochenek, Iman Ghasemi, Christoph B. Wiedenroth, Olympia Bikou, Ioannis Karampinis, Eric D. Roessner, Lukas Hobohm, Stefan Guth, Philipp Lurz, Stavros Konstantinides, Katrin Schäfer   +10 more
wiley   +1 more source

Endothelin System in Hypertension and Chronic Kidney Disease. [PDF]

Hypertension
Schiffrin EL, Pollock DM.
europepmc   +1 more source

Isolated Anti‐SS‐A Antibody Seropositivity as a Poor Prognostic Factor in Systemic Sclerosis: Insights From a Cohort of 307 Cases

The Journal of Dermatology, Volume 53, Issue 1, Page 41-53, January 2026.
ABSTRACT Systemic sclerosis is an autoimmune disease characterized by vasculopathy, fibrosis, and immune dysregulation. Anti‐SS‐A antibodies (anti‐SSA) have been reported to confer severe clinical manifestations in some Western and Japanese cohorts. We aimed to determine whether anti‐SSA seropositivity affects clinical outcomes in Japanese patients. We
Nana Ishida, Kazuki M. Matsuda, Hirohito Kotani, Hayakazu Sumida, Shinichi Sato   +4 more
wiley   +1 more source

HAMPAO-SPECT of the brain and ocular microangiopathic syndrome in patients infected with the human immunodeficiency virus type 1 [PDF]

, 1993
Bogner, Johannes R., Einhäupl, Karl Max, Geier, Stephan A., Goebel, Frank-Detlef, Hammel, Gertrud, Sadri, Ifna, Schielke, Eva, Tatsch, Klaus   +7 more
core  

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

British Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 58-72, January 2026.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post, Cayla Denney, Adam Cohen, Jens Jordan, Ulrich Limper   +4 more
wiley   +1 more source

Astrocytic ET-1 System Determines Microglia Phenotype Following Spinal Cord Injury. [PDF]

Adv Sci (Weinh)
He B, Xu S, Li M, Li H, Li S, Niu L, Song H, Cai R, Zhou Y, Cao Z, Wang Y, Wang Y.   +11 more
europepmc   +1 more source

UPREGULATION OF ENDOTHELIN (ETA AND ETB) RECEPTORS AND DOWN REGULATION OF NITRIC OXIDE SYNTHASE IN THE DETRUSOR OF A RABBIT MODEL OF BLADDER OUTLET OBSTRUCTION

, 1999
Cecil S. Thompson, Masood Khan, Mick Dashwood, Faiz Mumtaz, Dimitri P. Mikhailidis, Robert Morgan   +5 more
openalex   +1 more source

Addressing unmet needs for chronic kidney disease treatment in type 1 diabetes: A review

Diabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 16-26, January 2026.
Abstract Chronic kidney disease (CKD) is a serious complication occurring in nearly one of three people with type 1 diabetes (T1D). Major therapeutic advances have been made in the management of CKD for people with type 2 diabetes (T2D), thereby improving their kidney, cardiovascular, and survival outcomes.
Katherine R. Tuttle, Linong Ji, Chantal Mathieu, Jonathan Rosen   +3 more
wiley   +1 more source

Plasma Endothelin-1 Levels: Non-Predictors of Alzheimer's Disease Reveal Age Correlation in African American Women. [PDF]

J Clin Med
Zagol-Ikapitte IA, Tabatabai MA, Wilus DM, Alcendor DJ.   +3 more
europepmc   +1 more source