Results 91 to 100 of about 36,043 (285)
Corneal stromal demarcation line after collagen cross-linking in corneal ectatic diseases: a review of the literature [PDF]
, 2016 Collagen cross-linking (CXL) is a relatively new conservative approach for progressive corneal ectasia, which is able to strengthen corneal tissue reforming new covalent bonds.
SPADEA, LEOPOLDO +2 more
core +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Following anterior cruciate ligament (ACL) reconstruction, enhancing hamstring tenocyte activity and minimizing apoptosis are critical for preventing graft failure and promoting ligamentization. This study investigated the therapeutic potential of extracellular vesicles (EVs) derived from a coculture of ACL remnant cells and bone marrow ...
Hon‐Lok Lo +5 more
wiley +1 more source
Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
Med Research, EarlyView.The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley +1 more source
Effects of Laser In Situ Keratomileusis on the Corneal Endothelium
Kaohsiung Journal of Medical Sciences, 2005 The purpose of this study was to assess the effects of laser in situ keratomileusis (LASIK) on the corneal endothelium. In a prospective study, the corneal endothelium of 87 eyes (45 patients) was examined before and 1 month after LASIK.
Chun-Chi Chiang +4 more
doaj +1 more source
Next generation tyrosine-mutant AAV8 shows high mouse corneal endothelial transduction in vivo [abstract] [PDF]
, 2010 Purpose: Recently, point mutations in surface-exposed tyrosine residues have been shown to increase AAV transduction significantly. We examined the efficacy of conventional AAV8 and next generation tyrosine-mutant AAV8 vectors to deliver genes into ...
Tovey, Jonathan
core
The Immunological Basis of Dry Eye Disease and Current Topical Treatment Options. [PDF]
, 2020 Homeostasis of the lacrimal functional unit is needed to ensure a well-regulated ocular immune response comprising innate and adaptive phases. When the ocular immune system is excessively stimulated and/or immunoregulatory mechanisms are disrupted, the ...
Lin, Meng C +4 more
core +1 more source
Biodegradable Natural Polymer‐Based Drug Delivery Systems for Bone Tissue Engineering
Medicinal Research Reviews, EarlyView.ABSTRACT The increasing incidence of bone diseases and injuries, especially among aging populations, has underscored the shortcomings of traditional treatments such as bone grafts and metal implants, which often face complications including immune rejection, mechanical failure, and delayed healing.
Hyejin Jo +4 more
wiley +1 more source
Regulation of Oxidative Stress in Corneal Endothelial Cells by Prdx6
Antioxidants, 2018 The inner layer of the cornea, the corneal endothelium, is post-mitotic and unable to regenerate if damaged. The corneal endothelium is one of the most transplanted tissues in the body.
Matthew Lovatt +3 more
doaj +1 more source
Refractive change following pseudophakic vitrectomy: a retrospective review [PDF]
, 2008 Background To assess the occurrence and magnitude of refractive change in pseudophakic eyes undergoing 20 gauge pars plana vitrectomy without scleral buckling and to investigate possible aetiological factors.
Anthony Hildreth +19 more
core +5 more sources
The Journal of Pathology, EarlyView.Abstract Late‐onset Fuchs endothelial corneal dystrophy (FECD) is commonly framed as a corneal endothelial disease characterised by guttae accumulation and progressive thickening of Descemet's membrane (DM). However, clinical forms and evolutionary profiles vary widely.
Sayo Maeno +3 more
wiley +1 more source