Results 11 to 20 of about 161,906 (230)

Substrates for Expansion of Corneal Endothelial Cells towards Bioengineering of Human Corneal Endothelium

Journal of Functional Biomaterials, 2015
Corneal endothelium is a single layer of specialized cells that lines the posterior surface of cornea and maintains corneal hydration and corneal transparency essential for vision.
Jesintha Navaratnam, Tor P. Utheim, Vinagolu K. Rajasekhar, Aboulghassem Shahdadfar   +3 more
doaj   +2 more sources

Constructing a Novel Three-Dimensional Biomimetic Corneal Endothelium Graft by Culturing Corneal Endothelium Cells on Compressed Collagen Gels

Chinese Medical Journal, 2018
Background: Endothelium allotransplantation is the primary treatment for corneal decompensation. The worldwide shortage of donor corneal tissue has led to increasing pressure to seek an alternative for surgical restoration of corneal endothelium ...
Yu-Jie Cen, Yun Feng
doaj   +2 more sources

Effects of Aberrant Pax6 Gene Dosage on Mouse Corneal Pathophysiology and Corneal Epithelial Homeostasis [PDF]

, 2011
Background: Altered dosage of the transcription factor PAX6 causes multiple human eye pathophysiologies. PAX6(+/-) heterozygotes suffer from aniridia and aniridia-related keratopathy (ARK), a corneal deterioration that probably involves a limbal ...
Fullwood, Nigel J., Martin, Francis L., Collinson, J. Martin, Richard L Mort, Morley, Steven D., Morley Steven D., West John D., Bentley, Adam J., Adam J Bentley, Mort, Richard L, Collinson J. Martin, Panagiotis Douvaras, Collinson, J Martin, J Martin Collinson, Bentley Adam J., Mort Richard L., Martin, Francis L, Bentley, Adam J, Morley, Steven D, Martin Francis L., Douvaras, Panagiotis, Steven D Morley, Robert E Hill, Mort, Richard L., West, John D., Hill, Robert E, Fullwood, Nigel J, Nigel J Fullwood, Douvaras Panagiotis, Fullwood Nigel J., Francis L Martin, Hill Robert E., Hill, Robert E., West, John D, John D West   +34 more
core   +5 more sources

Injury induces endothelial to mesenchymal transition in the mouse corneal endothelium in vivo via FGF2

Molecular Vision, 2019
Purpose: To determine whether the mouse corneal endothelium enters endothelial to mesenchymal transition (EndoMT) following surgical injury in vivo. Methods: The corneal endothelium in anesthetized mice was surgically injured in vivo under direct ...
JeongGoo Lee, Eric Jung, Martin Heur
doaj   +1 more source

Immune cells on the corneal endothelium of an allogeneic corneal transplantation rabbit model [PDF]

, 2017
PURPOSE. Corneal endothelial cell density undergoes a progressive decrease for many years after transplantation, eventually threatening patients with late endothelial failure. The purpose of this study was to investigate the possibility of an immunologic
Fullwood, Nigel J., Koizumi, Noriko, Okumura, Naoki, Okazaki, Yugo, Hori, Junko, Koudouna, Elena, Kinoshita, Shigeru, Nakano, Shinichiro, Inoue, Ryota   +8 more
core   +5 more sources

Nanoneedles Induce Targeted siRNA Silencing of p16 in the Human Corneal Endothelium

Advanced Science, 2022
Nanoneedles can target nucleic acid transfection to primary cells at tissue interfaces with high efficiency and minimal perturbation. The corneal endothelium is an ideal target for nanoneedle‐mediated RNA interference therapy aimed at enhancing its ...
Eleonora Maurizi, Davide Alessandro Martella, Davide Schiroli, Alessia Merra, Salman Ahmad Mustfa, Graziella Pellegrini, Claudio Macaluso, Ciro Chiappini   +7 more
doaj   +1 more source

Specular microscopy of the corneal endothelial cells of bovines: An ex vivo study

Open Veterinary Journal, 2023
Background: The endothelium is the most posterior layer of the cornea and essential for maintaining corneal transparency. Due to variations in corneal endothelial parameters among different species, knowledge of the normal parameters for each species is
Mariane Gallicchio Azevedo, Natalia Pons Mendez, Luísa Soares Cargnin, Rafaella Silva Rocha, Maiara Poersch Seibel, Alessandra Fernandez da Silva, Joao Antonio Tadeu Pigatto   +6 more
doaj   +1 more source

Comparison of Corneal Endothelium in Patients with Uveitis and Healthy Subjects Using Specular Microscopy

Pakistan Armed Forces Medical Journal, 2022
Objective: To evaluate changes in corneal endothelium in patients with anterior uveitis by using specular microscopy and compare it with the corneal endothelium of healthy subjects. Study Design: Comparative cross-sectional study.
Qurat ul Ain Ghazanfar, Omar Zafar, Noman Nazir Ahmed, Muhammad Manzoor Awan   +3 more
doaj   +1 more source

Oligopeptide-mediated gene transfer into mouse corneal endothelial cells: Expression, design optimization, uptake mechanism and nuclear localization [PDF]

, 2009
Copyright © The Author 2009. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses?by-nc/2.0/uk/) which permits ...
Seow, WY, George, AJT, Yang, Y-Y
core   +1 more source

Factors affecting the corneal endothelium after selective laser trabeculoplasty in primary open angle and angle closure glaucoma

BMJ Open Ophthalmology, 2021
Purpose To study the factors affecting the corneal endothelium after selective laser trabeculoplasty (SLT) in primary open angle glaucoma (POAG) and primary angle closure glaucoma (PACG).Method This prospective interventional study included 56 patients ...
Natalia Ivanovna Kurysheva, Lyudmila Vyacheslavovna Lepeshkina, Svetlana Georgievna Kapkova   +2 more
doaj   +1 more source