Results 181 to 190 of about 145,699 (299)

Engineered immunostimulatory H2O2‐producing microreactors driven by yeast as localized living cancer therapeutics

BMEMat, EarlyView.
Engineered yeast microreactors that produce H2O2 within tumors enable selective cancer cell killing while releasing immunostimulatory components, effectively suppressing local tumor growth and activating systemic antitumor immunity, with further efficacy enhanced by anti‐PD‐1 therapy and transarterial embolization.
Wenqian He, Chunjie Wang, Minming Chen, Weihao Yang, Bin Yu, Yuhang Hu, Hengze Ding, Yifan Yan, Zhijuan Yang, Liangzhu Feng   +9 more
wiley   +1 more source

Glycan targeting can recruit anti-tumor immunologic functions by lymphatic endothelium. [PDF]

Neoplasia
Dash A, Johns SC, Moleta C, Zúñiga EI, Fuster MM.   +4 more
europepmc   +1 more source

Epithelioid Enigma: Proximal‐Type Epithelioid Sarcoma in Cyst Fluid Cytology

Diagnostic Cytopathology, EarlyView.
ABSTRACT Epithelioid sarcoma (ES) is a rare, aggressive soft tissue malignancy with substantial morphologic overlap with other epithelioid neoplasms, creating diagnostic difficulty in cytology specimens. We report proximal‐type ES identified in cyst fluid from a lesion clinically interpreted as an epidermal inclusion cyst or abscess.
Nathan McGrath, Azfar Neyaz, Samer Khader   +2 more
wiley   +1 more source

Dermatomal Microcycstic Lymphatic Malformation: A Case Report of an Unusual Presentation. [PDF]

Clin Cosmet Investig Dermatol
Alzhrani G, Alhawsawi W, Alzaidi R, Alghamdi FA, Alghamdi B, Makhdoum S.   +5 more
europepmc   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Oral Hobnail Hemangioma of the Maxillary Labial Mucosa: Clinicopathologic Findings of a Rare Case. [PDF]

Case Rep Dent
Dinç K, Yaşar F, Çelik M.
europepmc   +1 more source

Autonomous Nanomedicine: Closing the Biological Validation Gap

Exploration, EarlyView.
Delivery of nanoparticles to tumors has not improved in over fifteen years, and biological testing remains slow and separate from formulation design. This review proposes adding a Biology step to the design cycle, using organ chips and patient‐derived organoids, and assesses the readiness of each required technology.
Yan Jun Lin, Izabella Komperda
wiley   +1 more source

From Somatic Driver to Molecular Therapy in Retinal, Choroidal and Periocular Vascular Disease: Mosaicism, Targetable Pathways and Ocular Toxicity. [PDF]

Int J Mol Sci
Adamski W.
europepmc   +1 more source

Oral Bacterial Extracellular Vesicles as Systemic Messengers: A Mouth–Gut–Systemic Axis Paradigm

Gut Medicine, EarlyView.
ABSTRACT Oral microbiome dysbiosis not only associated with localized periodontal disease but also with multiple systemic diseases, including cardiovascular disease, diabetes mellitus, Alzheimer's disease, rheumatoid arthritis, and cancer. However, the efficiency with which intact viable bacteria cross biological barriers to reach distant organs is ...
Yaping Huang, Narisu Hu, Shuang Pan, Sohaib Shujaat, Zhihui Tang, Hongyang Ma   +5 more
wiley   +1 more source

3D chromatin organisation contributes to the regulatory logic in differentiating lymphatic endothelium. [PDF]

EMBO Rep
Panara V, Arnold H, Gloger M, Skoczylas R, Vidal Gutierrez V, Johansson A, Smialowska A, Koltowska K.   +7 more
europepmc   +1 more source