Results 61 to 70 of about 266,603 (335)

Podoplanin immunopositive lymphatic vessels at the implant interface in a rat model of osteoporotic fractures [PDF]

, 2013
Insertion of bone substitution materials accelerates healing of osteoporotic fractures. Biodegradable materials are preferred for application in osteoporotic patients to avoid a second surgery for implant replacement. Degraded implant fragments are often
Alt, Volker, Gelinsky, Michael, Hanke, Thomas, Hartmann, Sonja, Heinemann, Sascha, Heiss, Christian, Kampschulte, Marian, Kauschke, Vivien, Kautz, Armin R., Kilian, Olaf, Langheinrich, Alexander, Lips, Katrin Susanne, Ray, Seemun, Schnabelrauch, Matthias, Schnettler, Reinhard, Schumacher, Matthias, Thormann, Ulrich   +16 more
core   +8 more sources

Initial afferent lymphatic vessels controlling outbound leukocyte traffic from skin to lymph nodes.

Frontiers in Immunology, 2013
Tissue drains fluid and macromolecules through lymphatic vessels, which are lined by a specialized endothelium that expresses peculiar differentiation proteins, not found in blood vessels (i.e: LYVE-1, Podoplanin, PROX-1 and VEGFR-3).
Ignacio eMelero, Alvaro eTeijeira, Ana eRouzaut   +2 more
doaj   +1 more source

KSHV Induction of Angiogenic and Lymphangiogenic Phenotypes

Frontiers in Microbiology, 2012
Kaposi’s Sarcoma is a highly vascularized tumor supporting large amounts of neo-angiogenesis. The major cell type in KS tumors is the spindle cell, a cell that expresses markers of lymphatic endothelium. KSHV, the etiologic agent of KS, is found in the
Terri A. DiMiao, Michael eLagunoff
doaj   +1 more source

Apelin modulates pathological remodeling of lymphatic endothelium after myocardial infarction.

JCI Insight, 2017
Lymphatic endothelium serves as a barrier to control fluid balance and immune cell trafficking to maintain tissue homeostasis. Long-term alteration of lymphatic vasculature promotes edema and fibrosis, which is an aggravating factor in the onset of ...
Florence Tatin, Edith Renaud-Gabardos, Anne-Claire Godet, Fransky Hantelys, F. Pujol, F. Morfoisse, D. Calise, Fanny Viars, P. Valet, B. Masri, A. Prats, B. Garmy-Susini   +11 more
semanticscholar   +1 more source

Microfluidic‐Based Reconstitution of Functional Lymphatic Microvasculature: Elucidating the Role of Lymphatics in Health and Disease

Advancement of science, 2023
The knowledge of the blood microvasculature and its functional role in health and disease has grown significantly attributable to decades of research and numerous advances in cell biology and tissue engineering; however, the lymphatics (the secondary ...
J. C. Serrano, M. Gillrie, Ran Li, Sarah H. Ishamuddin, Emad Moeendarbary, R. Kamm   +5 more
semanticscholar   +1 more source

PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration

Nature Communications, 2022
The Programmed death-1 (PD-1) and its ligand PD-L1 are critical checkpoints in the regulation of immune responses. Here the authors implicate PD-L1 signalling at lymphatic endothelium in the regulation of transendothelial migration of T cells.
Wenji Piao, Lushen Li, Vikas Saxena, Jegan Iyyathurai, Ram Lakhan, Yigang Zhang, Isadora Tadeval Lape, Christina Paluskievicz, Keli L. Hippen, Young Lee, Emma Silverman, Marina W. Shirkey, Leonardo V. Riella, Bruce R. Blazar, Jonathan S. Bromberg   +14 more
doaj   +1 more source

Insulin resistance disrupts cell integrity, mitochondrial function, and inflammatory signaling in lymphatic endothelium

Microcirculation, 2018
Lymphatic vessel dysfunction and increased lymph leakage have been directly associated with several metabolic diseases. However, the underlying cellular mechanisms causing lymphatic dysfunction have not been determined. Aberrant insulin signaling affects
Yang Lee, Sanjukta Chakraborty, C. Meininger, M. Muthuchamy   +3 more
semanticscholar   +1 more source

Lymphatic Endothelial-to-Myofibroblast Transition: A Potential New Mechanism Underlying Skin Fibrosis in Systemic Sclerosis

Cells, 2023
At present, only a few reports have addressed the possible contribution of the lymphatic vascular system to the pathogenesis of systemic sclerosis (SSc).
I. Rosa, E. Romano, B. Fioretto, K. El Aoufy, S. Bellando-Randone, M. Matucci-Cerinic, M. Manetti   +6 more
semanticscholar   +1 more source

The Road Less Traveled: Regulation of Leukocyte Migration Across Vascular and Lymphatic Endothelium by Galectins [PDF]

, 2010
Leukocyte entry from the blood into inflamed tissues, exit into the lymphatics, and migration to regional lymph nodes are all crucial processes for mounting an effective adaptive immune response.
AB Dietz, AD Luster, AG Harmsen, BA Maletto, BN Stillman, C Colnot, CD Gil, CD Gil, CF Brewer, CR Mackay, D Alvarez, DC Anderson, DK Hsu, DK Hsu, FT Liu, GA Rabinovich, GA Rabinovich, GA Rabinovich, GA Rabinovich, GJ Randolph, GR Vasta, H Sano, H Yamamoto, IJ Chen, J Almkvist, J He, J Nieminen, J Saegusa, JA Fulcher, JA Fulcher, JD Hernandez, JT Nguyen, K Furukawa, K Ley, KE Pace, LA Earl, LA Earl, LA Johnson, LA Johnson, LG Baum, Linda G. Baum, LN Cueni, LN Cueni, LV Norling, M Amano, M Demetriou, M Hirashima, M La, M Nachtigal, M Nagae, MA Daniels, MA Daniels, MA Pozo del, MK Wild, ML Hermiston, ML Thomas, MT Elola, N Ahmad, N Demotte, N Matsushita, N Rubinstein, NL Perillo, OB Garner, Q Huang, RI Zuberi, S Bi, S Bi, S Rifat, S Sato, Sandra Thiemann, SD Liu, SK Cha, SR Stowell, SR Stowell, V Abadie, VL Thijssen, VS Erickson, WN Haining, X Song, Y Tsuboi   +79 more
core   +2 more sources

Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway

Nature Communications, 2021
Different types of mesenchymal progenitors participate in ectopic bone formation. Here, the authors show Col2+ lineage cells adopt a lymphatic endothelium cell fate, which regulates local inflammatory microenvironment after trauma, thus influencing ...
Dali Zhang, Junlan Huang, Xianding Sun, Hangang Chen, Shuo Huang, Jing Yang, Xiaolan Du, Qiaoyan Tan, Fengtao Luo, Ruobin Zhang, Siru Zhou, Wanling Jiang, Zhenhong Ni, Zuqiang Wang, Min Jin, Meng Xu, Fangfang Li, Liang Chen, Mi Liu, Nan Su, Xiaoqing Luo, Liangjun Yin, Ying Zhu, Jerry Q. Feng, Di Chen, Huabing Qi, Lin Chen, Yangli Xie   +27 more
doaj   +1 more source