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Cells with Many Talents: Lymphatic Endothelial Cells in the Brain Meninges [PDF]
Cells, 2021 The lymphatic system serves key functions in maintaining fluid homeostasis, the uptake of dietary fats in the small intestine, and the trafficking of immune cells. Almost all vascularized peripheral tissues and organs contain lymphatic vessels. The brain
Irina Suárez, Stefan Schulte-Merker
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Plasticity of blood- and lymphatic endothelial cells and marker identification. [PDF]
PLoS ONE, 2013 The distinction between lymphatic and blood vessels is biologically fundamental. Here we wanted to rigorously analyze the universal applicability of vascular markers and characteristics of the two widely used vascular model systems human microvascular ...
Johannes Keuschnigg +8 more
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TGF-β signaling in lymphatic vascular vessel formation and maintenance
Frontiers in Physiology, 2022 Transforming growth factor (TGF)-β and its family members, including bone morphogenetic proteins (BMPs), nodal proteins, and activins, are implicated in the development and maintenance of various organs. Here, we review its role in the lymphatic vascular
Fumiko Itoh, Tetsuro Watabe
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Tolerogenic properties of lymphatic endothelial cells are controlled by the lymph node microenvironment. [PDF]
PLoS ONE, 2014 Peripheral self-tolerance eliminates lymphocytes specific for tissue-specific antigens not encountered in the thymus. Recently, we demonstrated that lymphatic endothelial cells in mice directly express peripheral tissue antigens, including tyrosinase ...
Jarish N Cohen +8 more
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Fine filaments in lymphatic endothelial cells [PDF]
The Journal of Cell Biology, 1976 Several and various types of cells contain fine cytoplasmic filaments closely resembling the myofilaments of muscle cells (2, 18, 23, 24). In many of these cells and especially when cultured, it has been demonstrated that some of these filaments react with heavy meromyosin (HMM) in the same way as do the actin filaments of muscle cells (3, 6 7).
J M, Lauweryns, J, Baert, W, De Loecker
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Molecular characterization of lymphatic endothelial cells [PDF]
Proceedings of the National Academy of Sciences, 2002 The lymphatic microvasculature is uniquely adapted for the continuous removal of interstitial fluid and proteins and is an important entry point for leukocytes and tumor cells. Specialized functions of lymphatics suggest differences in the molecular composition of the lymphatic and blood vascular endothelium.
Simona Podgrabinska +6 more
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Cells, 2023 At present, only a few reports have addressed the possible contribution of the lymphatic vascular system to the pathogenesis of systemic sclerosis (SSc).
Irene Rosa +6 more
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Heterogeneity and Plasticity of Lymphatic Endothelial Cells [PDF]
Seminars in Thrombosis and Hemostasis, 2010 Endothelial cells are found in most organs and tissues in our body. Despite their apparent morphological and functional similarities, endothelial cells exhibit remarkable heterogeneity and plasticity. In a strict sense, no two endothelial cells are identical in terms of their biological, immunological, functional, metabolic, morphological, and ...
Sunju, Lee, Inho, Choi, Young-Kwon, Hong
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Current Issues in Molecular Biology, 2022 In our previous study, we found that lymphatic vessels stimulate hair follicle growth through paracrine effects on dermal papilla cells. However, the paracrine factors secreted from cutaneous lymphatic vessels that can activate dermal papilla cells are ...
Sun-Young Yoon, Michael Detmar
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Aberrant lymphatic endothelial progenitors in lymphatic malformation development.
PLoS ONE, 2015 Lymphatic malformations (LMs) are vascular anomalies thought to arise from dysregulated lymphangiogenesis. These lesions impose a significant burden of disease on affected individuals.
June K Wu +10 more
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