Results 41 to 50 of about 5,011,546 (295)
A critical role for lymphatic endothelial heparan sulfate in lymph node metastasis
Molecular Cancer, 2010 Background Lymph node metastasis constitutes a key event in tumor progression. The molecular control of this process is poorly understood. Heparan sulfate is a linear polysaccharide consisting of unique sulfate-modified disaccharide repeats that allow ...
Srinivasan R Sathish +6 more
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Scientific Reports, 2022 Claudin-3 is a tight junction protein that has often been associated with the progression and metastasis of various tumors. Here, the role of claudin-3 in tumor-induced lymphangiogenesis is investigated.
Ningjing Lei +9 more
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Regulation of lymphatic-blood vessel separation by endothelial Rac1 [PDF]
, 2009 Sprouting angiogenesis and lymphatic-blood vessel segregation both involve the migration of endothelial cells, but the precise migratory molecules that govern the decision of blood vascular endothelial cells to segregate into lymphatic vasculature are ...
Hodivala-Dilke, Kairbaan M. +23 more
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Mobilization of lymphatic endothelial precursor cells and lymphatic neovascularization in primary Sjögren's syndrome [PDF]
Journal of Cellular and Molecular Medicine, 2016 Abstract Although lymphatic neovascularization may be a key feature of chronic inflammation, it is almost unexplored in primary Sjögren's syndrome ( pSS ). A recent study revealed a pro‐lymphangiogenic function of interleukin ( IL )‐17,
Alunno, Alessia +6 more
openaire +5 more sources
VEGF family members : modulators of tumor angiogenesis and lymphangiogenesis [PDF]
, 2006 Members of the vascular endothelial growth factor (VEGF) family and their receptors (VEGFR) play an essential role in the development and maintenance of the blood and lymphatic vasculature.
Kopfstein, Lucie
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The contribution of bone marrow-derived cells to angiogenesis and lymphangiogenesis in murine models of carcinogenesis [PDF]
, 2009 Cancer is a class of diseases in which a group of cells display uncontrolled growth (division beyond the normal limits), invasion (intrusion on and destruction of adjacent tissues), and sometimes metastasis (spread to other locations in the body via ...
Zumsteg, Adrian
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Isolation and Characterization of Human Lung Lymphatic Endothelial Cells [PDF]
BioMed Research International, 2015 Characterization of lymphatic endothelial cells from the respiratory system may be crucial to investigate the role of the lymphatic system in the normal and diseased lung. We describe a simple and inexpensive method to harvest, isolate, and expand lymphatic endothelial cells from the human lung (HL-LECs).
LORUSSO, BRUNO +15 more
openaire +4 more sources
eLife, 2017 The lymphatic system controls fluid homeostasis and the clearance of macromolecules from interstitial compartments. In mammals brain lymphatics were only recently discovered, with significant implications for physiology and disease. We examined zebrafish
Max van Lessen +5 more
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Cellular Physiology and Biochemistry, 2017 Background: Recent evidence has indicated that long non-coding RNA (lncRNA) is involved in the pathogenesis of type 2 diabetes, but nothing is known about lncRNA expression changes of lymphatic endothelial cells in response to type 2 diabetes.
Min Qi +9 more
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Lymphatic endothelial progenitors originate from plastic myeloid cells activated by toll-like receptor-4. [PDF]
PLoS ONE, 2017 Myeloid-derived lymphatic endothelial cells (M-LECP) are induced by inflammation and play an important role in adult lymphangiogenesis. However, the mechanisms driving M-LECP differentiation are currently unclear.
Lisa D Volk-Draper +3 more
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