Results 61 to 70 of about 5,011,546 (295)

KSHV infection of endothelial precursor cells with lymphatic characteristics as a novel model for translational Kaposi’s sarcoma studies [PDF]

, 2023
Kaposi’s sarcoma herpesvirus (KSHV) is the etiologic agent of Kaposi’s sarcoma (KS), a hyperplasia consisting of enlarged malformed vasculature and spindle-shaped cells, the main proliferative component of KS.
Tuohinto, Krista, Karnezis, Tara P., Kiss, Elina A., Terri A DiMaio, Elina A Kiss, Pirjo Laakkonen, Lagunoff, Michael, DiMaio, Terri A., Laakkonen, Pirjo, Laakkonen, Pirjo P., Michael Lagunoff, Kiss, Elina, Saharinen, Pipsa, Ojala, Päivi M., Krista Tuohinto, Tara Karnezis, Pipsa Saharinen, DiMaio, Terri P., Ojala, Päivi M. P., Päivi M Ojala, Karnezis, Tara, Päivi M. Ojala, Terri A. DiMaio, Elina A. Kiss   +23 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Brugia malayi Asparaginyl-tRNA Synthetase Stimulates Endothelial Cell Proliferation, Vasodilation and Angiogenesis. [PDF]

PLoS ONE, 2016
A hallmark of chronic infection with lymphatic filarial parasites is the development of lymphatic disease which often results in permanent vasodilation and lymphedema, but all of the mechanisms by which filarial parasites induce pathology are not known ...
Jeeva Jothi D, Muthu Dhanraj, Shanmugam Solaiappan, Sanjana Sivanesan, Michael Kron, Anuradha Dhanasekaran   +5 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Expression of molecular lymphatic markers in human choroid

Acta Biomedica Scientifica, 2016
The purpose of this study was to research lymphatic outflow tract in the human choroid. Using a light microscopy and immunohistochemistry, structure of the choroid was investigated. We used antibodies against lymphatic endothelial-specific markers Prox-1,
S. R. Nogovitsina
doaj   +1 more source

PEDF inhibits lymphatic metastasis of nasopharyngeal carcinoma as a new lymphangiogenesis inhibitor

Cell Death and Disease, 2021
Nasopharyngeal carcinoma (NPC) is one of the most malignant tumors in southern China and Asia, and lymph node metastasis is an important cause for treatment failure.
Chuanghua Luo, Haofan Yin, Tianxiao Gao, Caiqi Ma, Junxi Liu, Ting Zhang, Zumin Xu, Xi Wang, Danrui Zhang, Weiwei Qi, Zhonghan Yang, Guoquan Gao, Xia Yang, Ti Zhou   +13 more
doaj   +1 more source

Lymphatic and vascular endothelial cells in NEC exhibit proinflammatory signatures.

, 2023
(A) Re-clustered atlas of the lymphatic and vascular endothelial cluster. (B) Single-cell atlas annotated by condition. (C) Top 8 markers of the markers for the cell types in A.
Jordan S. Pober (13913871), Lael Werner (8414109), Blake McCourt (14138703), Shalev Itzkovitz (21721), Fujing Wang (12075455), Tatiana Silva (7419971), Dror Shouval (3436574), Adi Egozi (11547698), Richard W. Pierce (2516263), Xiaojing An (14301042), Liza Konnikova (8771951), Kong Chen (350715), Oluwabunmi Olaloye (14578412)   +12 more
core   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

PMab-235: A monoclonal antibody for immunohistochemical analysis against goat podoplanin

Heliyon, 2019
Sensitive and specific monoclonal antibodies (mAbs) against not only human but also mouse, rat, rabbit, dog, cat, bovine, pig, and horse podoplanins (PDPNs) have been established in our previous studies.
Yoshikazu Furusawa, Shinji Yamada, Takuro Nakamura, Masato Sano, Yusuke Sayama, Shunsuke Itai, Junko Takei, Hiroyuki Harada, Masato Fukui, Mika K. Kaneko, Yukinari Kato   +10 more
doaj   +1 more source

Lymphatic endothelial cells are readily distinguished from vascular endothelial cells.

, 2013
The portal triad region of mouse liver was analyzed for the expression of lymphatic (Lyve-1, VEGFR-3) and vascular (CD31, vWF) endothelial cell markers, a macrophage marker (F4/80) and a pericyte/smooth muscle marker (α-SMA).
Philip R. Streeter (375686), Alexis S. Bailey (375683), John R. Swain (261517), Melissa H. Wong (261519), Devorah C. Goldman (190045), Shuguang Jiang (270417), William H. Fleming (190067)   +6 more
core   +1 more source