Results 1 to 10 of about 22,968 (143)

Hematopoietic stem cells contribute to lymphatic endothelium.

PLoS ONE, 2008
BackgroundAlthough the lymphatic system arises as an extension of venous vessels in the embryo, little is known about the role of circulating progenitors in the maintenance or development of lymphatic endothelium.
Shuguang Jiang, Alexis S Bailey, Devorah C Goldman, John R Swain, Melissa H Wong, Philip R Streeter, William H Fleming   +6 more
doaj   +3 more sources

Meningeal lymphatic-associated brain swelling in acute stroke. [PDF]

PLoS ONE
Brain meninges contain lymphatic vessels that play roles in clearance of extracellular solute in the central nervous system. But, whether and how the system is involved in acute stroke remains to be fully explored.
Rohan Mahesh Patil, Dong Bin Back, Gen Hamanaka, Rakhi Desai, Ayumi Hayakawa, Su Jing Chan, Bum Ju Ahn, Giuseppe Pignataro, Kazuhide Hayakawa, Elga Esposito   +9 more
doaj   +2 more sources

Immunomodulatory properties of the lymphatic endothelium in the tumor microenvironment

Frontiers in Immunology, 2023
The tumor microenvironment (TME) is an intricate complex and dynamic structure composed of various cell types, including tumor, stromal and immune cells.
Cristina Viúdez-Pareja, Cristina Viúdez-Pareja, Ewa Kreft, Ewa Kreft, Melissa García-Caballero, Melissa García-Caballero   +5 more
doaj   +3 more sources

Pannexin1 deletion in lymphatic endothelium affects lymphatic function in a sex‐dependent manner

Physiological Reports
The lymphatic network of capillaries and collecting vessels ensures tissue fluid homeostasis, absorption of dietary fats and trafficking of immune cells.
Avigail Ehrlich, Graziano Pelli, Robert Pick, Linda Clochard, Filippo Molica, Brenda R. Kwak   +5 more
doaj   +4 more sources

Connexin-45 is expressed in mouse lymphatic endothelium and required for lymphatic valve function

JCI Insight
The expression and functional relevance of the gap junction molecule connexin-45 (Cx45; GJC1) in lymphatic endothelium were not previously known. We found that Cx45 was expressed widely in the endothelium of murine lymphatics, in both valve and nonvalve ...
Michael J. Davis, Jorge A. Castorena-Gonzalez, Min Li, Scott D. Zawieja, Alex M. Simon, Xin Geng, R. Sathish Srinivasan   +6 more
doaj   +3 more sources

Lymphatic endothelium [PDF]

The Journal of Cell Biology, 2003
The lymphatic microvasculature is uniquely adapted for the continuous removal of interstitial fluid and proteins, and is an important point of entry for leukocytes and tumor cells. The traditional view that lymphatic capillaries are passive participants in these tasks is currently being challenged.
Michael S. Pepper, Mihaela Skobe
openaire   +3 more sources

Transcription Factor Control of Lymphatic Quiescence and Maturation of Lymphatic Neovessels in Development and Physiology

Frontiers in Physiology, 2021
The lymphatic system is a vascular system comprising modified lymphatic endothelial cells, lymph nodes and other lymphoid organs. The system has diverse, but critical functions in both physiology and pathology, and forms an interface between the blood ...
Zarah B. Tabrizi, Nada S. Ahmed, Joseph L. Horder, Sarah J. Storr, Andrew V. Benest   +4 more
doaj   +1 more source

Lymphatic Clearance of Immune Cells in Cardiovascular Disease

Cells, 2021
Recent advances in our understanding of the lymphatic system, its function, development, and role in pathophysiology have changed our views on its importance. Historically thought to be solely involved in the transport of tissue fluid, lipids, and immune
Christophe Ravaud, Nikita Ved, David G. Jackson, Joaquim Miguel Vieira, Paul R. Riley   +4 more
doaj   +1 more source

KSHV infection of endothelial precursor cells with lymphatic characteristics as a novel model for translational Kaposi's sarcoma studies.

PLoS Pathogens, 2023
Kaposi's sarcoma herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma (KS), a hyperplasia consisting of enlarged malformed vasculature and spindle-shaped cells, the main proliferative component of KS.
Krista Tuohinto, Terri A DiMaio, Elina A Kiss, Pirjo Laakkonen, Pipsa Saharinen, Tara Karnezis, Michael Lagunoff, Päivi M Ojala   +7 more
doaj   +1 more source

Lymphatic endothelium in health and disease [PDF]

Cell and Tissue Research, 2008
ISSN:1432 ...
Jurisic, Giorgia, Detmar, Michael
openaire   +4 more sources