Results 11 to 20 of about 43,399 (257)
The lymphatic microvasculature is uniquely adapted for the continuous removal of interstitial fluid and proteins, and is an important point of entry for leukocytes and tumor cells. The traditional view that lymphatic capillaries are passive participants in these tasks is currently being challenged.
Michael S. Pepper, Mihaela Skobe
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The Lymphatic Endothelium in the Context of Radioimmuno-Oncology
The study of lymphatic tumor vasculature has been gaining interest in the context of cancer immunotherapy. These vessels constitute conduits for immune cells’ transit toward the lymph nodes, and they endow tumors with routes to metastasize to the lymph nodes and, from them, toward distant sites.
Lucía Suárez +2 more
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Lymphatic endothelium in health and disease [PDF]
ISSN:1432 ...
Jurisic, Giorgia, Detmar, Michael
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The inflammatory response of lymphatic endothelium [PDF]
ISSN:1573 ...
Aebischer David +2 more
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Calcium and electrical dynamics in lymphatic endothelium [PDF]
Key points Endothelial cell function in resistance arteries integrates Ca2+ signalling with hyperpolarization to promote relaxation of smooth muscle cells and increase tissue blood flow. Whether complementary signalling occurs in lymphatic endothelium is unknown.
Erik J. Behringer +7 more
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Dendritic Cell Interactions with Lymphatic Endothelium [PDF]
Afferent lymphatic vessels fulfill essential immune functions by transporting leukocytes and lymph-borne antigen to draining lymph nodes (dLNs). An important cell type migrating through lymphatic vessels are dendritic cells (DCs). DCs reside in peripheral tissues like the skin, where they take up antigen and transport it via the lymphatic vascular ...
Russo Erica +2 more
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Paraxial Mesoderm Is the Major Source of Lymphatic Endothelium [PDF]
Endothelial cells (ECs), which line blood and lymphatic vessels, are generally described to come from the lateral plate mesoderm despite experimental evidence for a broader source of origin, including the paraxial mesoderm (PXM). Current dogma suggests that following specification from mesoderm, local environmental cues establish the distinct molecular
Stone, O., Stainier, D.
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The lymphatic endothelium of the avian wing is of somitic origin [PDF]
It has recently been shown that there are lymphangioblasts in the early avian wing bud, but fate map studies on the origin of these cells have not yet been performed. The lymphatics in the wings of 10-day-old chick and quail embryos are characterized by both the position along with all major blood vascular routes and by the Vascular Endothelial Growth ...
Wilting, Jörg +3 more
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Immunomodulatory properties of the lymphatic endothelium in the tumor microenvironment
The tumor microenvironment (TME) is an intricate complex and dynamic structure composed of various cell types, including tumor, stromal and immune cells. Within this complex network, lymphatic endothelial cells (LECs) play a crucial role in regulating immune responses and influencing tumor progression and metastatic dissemination to lymph node and ...
Cristina Viúdez-Pareja +5 more
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Cell Traffic and the Lymphatic Endothelium
The principal immune function of the afferent lymphatics is to bear antigen and leukocytes from peripheral tissues to the draining lymph nodes. Recent research has shown that passage of leukocytes into the afferent lymphatic capillaries is far from an indolent process; rather it is carefully orchestrated by an array of adhesion molecules, as well as by
Johnson, L, Jackson, D
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