Dendritic Cell Interactions with Lymphatic Endothelium [PDF]
Lymphatic Research and Biology, 2013 Afferent lymphatic vessels fulfill essential immune functions by transporting leukocytes and lymph-borne antigen to draining lymph nodes (dLNs). An important cell type migrating through lymphatic vessels are dendritic cells (DCs). DCs reside in peripheral tissues like the skin, where they take up antigen and transport it via the lymphatic vascular ...
Russo Erica +2 more
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Tumor-induced myeloid cell plasticity toward lymphatic endothelium [PDF]
, 2009 Tumor-associated lymphangiogenesis contributes to tumor progression by regulating interstitial fluid pressure, transporting immune cells to the tumor site and providing a route for metastatic dissemination.
Baeriswyl, Vanessa
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Paraxial Mesoderm Is the Major Source of Lymphatic Endothelium [PDF]
Developmental Cell, 2019 Endothelial cells (ECs), which line blood and lymphatic vessels, are generally described to come from the lateral plate mesoderm despite experimental evidence for a broader source of origin, including the paraxial mesoderm (PXM). Current dogma suggests that following specification from mesoderm, local environmental cues establish the distinct molecular
Stone, O., Stainier, D.
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Lymphatic vascular morphogenesis in development, physiology, and disease [PDF]
, 2011 The lymphatic vasculature constitutes a highly specialized part of the vascular system that is essential for the maintenance of interstitial fluid balance, uptake of dietary fat, and immune response. Recently, there has been an increased awareness of the
Amélie Sabine +9 more
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Endothelial Dysfunction: From a Pathophysiological Mechanism to a Potential Therapeutic Target
Biomedicines, 2021 The endothelium is considered the largest organ of the body, composed of a monolayer of endothelial cells (ECs) lining the interior surface of blood and lymphatic vessels [...]
Pasquale Ambrosino +2 more
doaj +1 more source
Expression of molecular lymphatic markers in human choroid
Acta Biomedica Scientifica, 2016 The purpose of this study was to research lymphatic outflow tract in the human choroid. Using a light microscopy and immunohistochemistry, structure of the choroid was investigated. We used antibodies against lymphatic endothelial-specific markers Prox-1,
S. R. Nogovitsina
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Role of Transcriptional and Epigenetic Regulation in Lymphatic Endothelial Cell Development
Cells, 2022 The lymphatic system is critical for maintaining the homeostasis of lipids and interstitial fluid and regulating the immune cell development and functions.
Hyeonwoo La +10 more
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A Role for All-Trans-Retinoic Acid in the Early Steps of Lymphatic Vasculature Development [PDF]
, 2010 The molecular mechanisms that regulate the earliest steps of lymphatic vascular system development are unknown. To identify regulators of lymphatic competence and commitment, we used an in vitro vascular assay with mouse embryonic stem cell-derived ...
Dabouras, Vasilios +11 more
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A critical role for lymphatic endothelial heparan sulfate in lymph node metastasis
Molecular Cancer, 2010 Background Lymph node metastasis constitutes a key event in tumor progression. The molecular control of this process is poorly understood. Heparan sulfate is a linear polysaccharide consisting of unique sulfate-modified disaccharide repeats that allow ...
Srinivasan R Sathish +6 more
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Imaging long-term fate of intramyocardially implanted mesenchymal stem cells in a porcine myocardial infarction model. [PDF]
PLoS ONE, 2011 The long-term fate of stem cells after intramyocardial delivery is unknown. We used noninvasive, repetitive PET/CT imaging with [(18)F]FEAU to monitor the long-term (up to 5 months) spatial-temporal dynamics of MSCs retrovirally transduced with the ...
Emerson C Perin +34 more
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