Results 31 to 40 of about 23,087 (262)

ULTRASTRUCTURAL ORGANIZATION OF THE LYMPHATIC CAPILLARIES IN CONJUNCTIVA AND THE LYMPHATIC CHANNELS IN HUMAN CHOROID

Сибирский научный медицинский журнал, 2019
The aim of this work was a comparative study of the ultrastructural organization of lymphatic structures in the choroid and conjunctiva of the human eye. Material and methods.
S. R. Nogovitsina, N. P. Bgatova, A. V. Eremina, A. N. Trunov, V. V. Chernykh, V. I. Konenkov   +5 more
doaj   +1 more source

Initial afferent lymphatic vessels controlling outbound leukocyte traffic from skin to lymph nodes.

Frontiers in Immunology, 2013
Tissue drains fluid and macromolecules through lymphatic vessels, which are lined by a specialized endothelium that expresses peculiar differentiation proteins, not found in blood vessels (i.e: LYVE-1, Podoplanin, PROX-1 and VEGFR-3).
Ignacio eMelero, Alvaro eTeijeira, Ana eRouzaut   +2 more
doaj   +1 more source

KSHV Induction of Angiogenic and Lymphangiogenic Phenotypes

Frontiers in Microbiology, 2012
Kaposi’s Sarcoma is a highly vascularized tumor supporting large amounts of neo-angiogenesis. The major cell type in KS tumors is the spindle cell, a cell that expresses markers of lymphatic endothelium. KSHV, the etiologic agent of KS, is found in the
Terri A. DiMiao, Michael eLagunoff
doaj   +1 more source

PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration

Nature Communications, 2022
The Programmed death-1 (PD-1) and its ligand PD-L1 are critical checkpoints in the regulation of immune responses. Here the authors implicate PD-L1 signalling at lymphatic endothelium in the regulation of transendothelial migration of T cells.
Wenji Piao, Lushen Li, Vikas Saxena, Jegan Iyyathurai, Ram Lakhan, Yigang Zhang, Isadora Tadeval Lape, Christina Paluskievicz, Keli L. Hippen, Young Lee, Emma Silverman, Marina W. Shirkey, Leonardo V. Riella, Bruce R. Blazar, Jonathan S. Bromberg   +14 more
doaj   +1 more source

Paraxial Mesoderm Is the Major Source of Lymphatic Endothelium [PDF]

Developmental Cell, 2019
Endothelial cells (ECs), which line blood and lymphatic vessels, are generally described to come from the lateral plate mesoderm despite experimental evidence for a broader source of origin, including the paraxial mesoderm (PXM). Current dogma suggests that following specification from mesoderm, local environmental cues establish the distinct molecular
Stone, O., Stainier, D.
openaire   +4 more sources

Cell Traffic and the Lymphatic Endothelium

Annals of the New York Academy of Sciences, 2008
The principal immune function of the afferent lymphatics is to bear antigen and leukocytes from peripheral tissues to the draining lymph nodes. Recent research has shown that passage of leukocytes into the afferent lymphatic capillaries is far from an indolent process; rather it is carefully orchestrated by an array of adhesion molecules, as well as by
Johnson, L, Jackson, D
openaire   +2 more sources

Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway

Nature Communications, 2021
Different types of mesenchymal progenitors participate in ectopic bone formation. Here, the authors show Col2+ lineage cells adopt a lymphatic endothelium cell fate, which regulates local inflammatory microenvironment after trauma, thus influencing ...
Dali Zhang, Junlan Huang, Xianding Sun, Hangang Chen, Shuo Huang, Jing Yang, Xiaolan Du, Qiaoyan Tan, Fengtao Luo, Ruobin Zhang, Siru Zhou, Wanling Jiang, Zhenhong Ni, Zuqiang Wang, Min Jin, Meng Xu, Fangfang Li, Liang Chen, Mi Liu, Nan Su, Xiaoqing Luo, Liangjun Yin, Ying Zhu, Jerry Q. Feng, Di Chen, Huabing Qi, Lin Chen, Yangli Xie   +27 more
doaj   +1 more source

Emerging roles of lymphatic endothelium in regulating adaptive immunity [PDF]

Journal of Clinical Investigation, 2014
Emerging research on the roles of stromal cells in modulating adaptive immune responses has included a new focus on lymphatic endothelial cells (LECs). LECs are presumably the first cells that come into direct contact with peripheral antigens, cytokines, danger signals, and immune cells travelling from peripheral tissues to lymph nodes.
Card Catherine M., Yu Shann S., Swartz Melody A.   +2 more
openaire   +2 more sources

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

LYVE-1 expression in the endothelium of newly formed vessels of carotid atherosclerotic plaque

Анналы клинической и экспериментальной неврологии, 2020
Introduction.The discovery of specific markers of lymphatic endothelium, including LYVE-1, has led to a much better understanding of the structure and function of the lymphatic system.
Anna N. Evdokimenko, Ksenia N. Kulichenkova, Tatiana S. Gulevskaya   +2 more
doaj   +1 more source