Results 51 to 60 of about 5,011,546 (295)

Conserved signaling through vascular endothelial growth (VEGF) receptor family members in murine lymphatic endothelial cells

open access: yes, 2011
Lymphatic vessels guide interstitial fluid, modulate immune responses by regulating leukocyte and antigen trafficking to lymph nodes, and in a cancer setting enable tumor cells to track to regional lymph nodes.
Williams, Elizabeth D.   +7 more
core   +1 more source

Locally Triggered Release of the Chemokine CCL21 Promotes Dendritic Cell Transmigration across Lymphatic Endothelia

open access: yesCell Reports, 2017
Summary: Trafficking cells frequently transmigrate through epithelial and endothelial monolayers. How monolayers cooperate with the penetrating cells to support their transit is poorly understood.
Kari Vaahtomeri   +7 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Morphological changes in lymphatic vessel endothelial cells.

open access: yes, 2013
Scanning electron microscopy (SEM) findings. (a) Lymphatic vessel endothelial cells protruding into the lymphatic lumen in the normal type. Bar = 10 µm. (b) Lymphangiectasia at its early stages.
Takeshi Todokoro (314536)   +13 more
core   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Mechanism of Alcohol Induced Mesenteric Lymphatic Vessel Leakage

open access: yesRevista Cubana de Investigaciones Biomédicas, 2020
Introduction: Lymphatic vessels are involved in the trafficking of immune cells and play a role in antigen transport and immune cell regulatory functions.
Flavia Souza-Smith   +3 more
doaj  

Contrasting phenotypes of the lymphatic endothelial cells and blood endothelial cells in human lymph nodes.

open access: yes, 2014
Contrasting phenotypes of the lymphatic endothelial cells and blood endothelial cells in human lymph nodes.
Claudia M. Mansell (551782)   +6 more
core   +1 more source

A translocated effector required for bartonella dissemination from derma to blood safeguards migratory host cells from damage by co-translocated effectors [PDF]

open access: yes, 2013
Numerous bacterial pathogens secrete multiple effectors to modulate host cellular functions. These effectors may interfere with each other to efficiently control the infection process.
Okujava, Rusudan   +54 more
core   +2 more sources

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

A short review on lymphatic endothelial cell heterogeneity

open access: yesInflammation and Regeneration, 2021
AbstractRecent single-cell RNA sequencing studies in mouse and human have clearly indicated that lymphatic endothelial cells (LECs) consist of multiple cell subsets, each expressing a unique set of genes, residing in distinct locations in the body. These studies have also revealed a conserved pattern of gene expression in LECs across animal species, as
openaire   +3 more sources

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