Results 51 to 60 of about 5,011,546 (295)
Lymphatic vessels guide interstitial fluid, modulate immune responses by regulating leukocyte and antigen trafficking to lymph nodes, and in a cancer setting enable tumor cells to track to regional lymph nodes.
Williams, Elizabeth D. +7 more
core +1 more source
Summary: Trafficking cells frequently transmigrate through epithelial and endothelial monolayers. How monolayers cooperate with the penetrating cells to support their transit is poorly understood.
Kari Vaahtomeri +7 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Morphological changes in lymphatic vessel endothelial cells.
Scanning electron microscopy (SEM) findings. (a) Lymphatic vessel endothelial cells protruding into the lymphatic lumen in the normal type. Bar = 10 µm. (b) Lymphangiectasia at its early stages.
Takeshi Todokoro (314536) +13 more
core +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Mechanism of Alcohol Induced Mesenteric Lymphatic Vessel Leakage
Introduction: Lymphatic vessels are involved in the trafficking of immune cells and play a role in antigen transport and immune cell regulatory functions.
Flavia Souza-Smith +3 more
doaj
Contrasting phenotypes of the lymphatic endothelial cells and blood endothelial cells in human lymph nodes.
Claudia M. Mansell (551782) +6 more
core +1 more source
A translocated effector required for bartonella dissemination from derma to blood safeguards migratory host cells from damage by co-translocated effectors [PDF]
Numerous bacterial pathogens secrete multiple effectors to modulate host cellular functions. These effectors may interfere with each other to efficiently control the infection process.
Okujava, Rusudan +54 more
core +2 more sources
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
A short review on lymphatic endothelial cell heterogeneity
AbstractRecent single-cell RNA sequencing studies in mouse and human have clearly indicated that lymphatic endothelial cells (LECs) consist of multiple cell subsets, each expressing a unique set of genes, residing in distinct locations in the body. These studies have also revealed a conserved pattern of gene expression in LECs across animal species, as
openaire +3 more sources

