Results 31 to 40 of about 109,302 (309)
MT1-MMP sheds LYVE-1 on lymphatic endothelial cells and suppresses VEGF-C production to inhibit lymphangiogenesis [PDF]
, 2016 Lymphangiogensis is involved in various pathological conditions, such as arthritis and cancer metastasis. Although many factors have been identified to stimulate lymphatic vessel growth, little is known about lymphangiogenesis inhibitors.
Cao, R +5 more
core +1 more source
Podoplanin immunopositive lymphatic vessels at the implant interface in a rat model of osteoporotic fractures [PDF]
, 2013 Insertion of bone substitution materials accelerates healing of osteoporotic fractures. Biodegradable materials are preferred for application in osteoporotic patients to avoid a second surgery for implant replacement. Degraded implant fragments are often
Alt, Volker +16 more
core +2 more sources
T Cell Migration from Inflamed Skin to Draining Lymph Nodes Requires Intralymphatic Crawling Supported by ICAM-1/LFA-1 Interactions. [PDF]
, 2017 T cells are the most abundant cell type found in afferent lymph, but their migration through lymphatic vessels (LVs) remains poorly understood. Performing intravital microscopy in the murine skin, we imaged T cell migration through afferent LVs in vivo ...
Coles, Marc +10 more
core +3 more sources
Lymphatic Endothelial Cell Plasticity in Development and Disease [PDF]
Physiology, 2017 The lymphatic vasculature is crucial for maintaining tissue-fluid homeostasis, providing immune surveillance and mediating lipid absorption. The lymphatic vasculature is tightly associated with the blood vasculature, although it exhibits distinct morphological and functional features.
Wanshu, Ma, Guillermo, Oliver
openaire +2 more sources
Molecular Medicine, 2020 Background Therapeutic lymphangiogenesis in an orthotopic lung transplant model has been shown to improve acute allograft rejection that is mediated at least in part through hyaluronan drainage.
Shikshya Shrestha +10 more
doaj +1 more source
Plasticity of blood- and lymphatic endothelial cells and marker identification. [PDF]
PLoS ONE, 2013 The distinction between lymphatic and blood vessels is biologically fundamental. Here we wanted to rigorously analyze the universal applicability of vascular markers and characteristics of the two widely used vascular model systems human microvascular ...
Johannes Keuschnigg +8 more
doaj +1 more source
Network development in biological gels: role in lymphatic vessel development [PDF]
, 2008 In this paper, we present a model that explains the prepatterning of lymphatic vessel morphology in collagen gels. This model is derived using the theory of two phase rubber material due to Flory and coworkers and it consists of two coupled fourth order ...
Fowler, A. C., Roose, Tiina
core +3 more sources
Cell Reports, 2023 Summary: Cardiac lymphatic vessels play important roles in fluid homeostasis, inflammation, disease, and regeneration of the heart. The developing cardiac lymphatics in human fetal hearts are closely associated with coronary arteries, similar to those in
Stanislao Igor Travisano +5 more
doaj +1 more source
A critical role for lymphatic endothelial heparan sulfate in lymph node metastasis
Molecular Cancer, 2010 Background Lymph node metastasis constitutes a key event in tumor progression. The molecular control of this process is poorly understood. Heparan sulfate is a linear polysaccharide consisting of unique sulfate-modified disaccharide repeats that allow ...
Srinivasan R Sathish +6 more
doaj +1 more source
Scientific Reports, 2022 Claudin-3 is a tight junction protein that has often been associated with the progression and metastasis of various tumors. Here, the role of claudin-3 in tumor-induced lymphangiogenesis is investigated.
Ningjing Lei +9 more
doaj +1 more source