Results 131 to 140 of about 605,396 (385)

SOX Transcription Factors in Endothelial Differentiation and Endothelial-Mesenchymal Transitions

open access: yesFrontiers in Cardiovascular Medicine, 2019
The SRY (Sex Determining Region Y)-related HMG box of DNA binding proteins, referred to as SOX transcription factors, were first identified as critical regulators of male sex determination but are now known to play an important role in vascular ...
Yucheng Yao   +3 more
doaj   +1 more source

The Endothelium and Hemodialysis [PDF]

open access: yes, 2011
The endothelium is a functional barrier composed of a single layer of endothelial cells between the vessel wall and circulating blood. The human vascular bed has a combined surface area of 1000 m2 and contains 1013 endothelial cells. The endothelium is the largest endocrine organ, with also important paracrine and autocrine functions (Perry & Pearson ...
openaire   +3 more sources

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

Premature vascular deterioration in young patients affected by Wilson’s disease: a pilot study

open access: yesJournal of Pediatric and Neonatal Individualized Medicine, 2017
Introduction: Wilson’s disease (WD) is a genetically inherited pathology which leads to an excessive deposition of copper in the human tissues, most of all in those of liver and brain.
Georgios Kouvelas   +5 more
doaj   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto   +5 more
wiley   +1 more source

Endothelial dysfunction in clinical practice: the role of laser Doppler flowmetry (literature review)

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2019
This literature review deals with endothelial dysfunction. Endothelial dysfunction is presented in noninfectious di­seases of the 21st century and at the same moment is a predictor of cardiovascular and cerebrovascular diseases, especially in patients ...
О.B. Dynnyk   +2 more
doaj   +1 more source

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

open access: yesFEBS Open Bio, EarlyView.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior   +5 more
wiley   +1 more source

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