Results 241 to 250 of about 335,896 (308)

A 3D Human Bone and Bone Marrow‐on‐a‐Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance

Advanced Science, EarlyView.
This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer, Melanie‐Jasmin Ort, Kristian Händler, Emely Bortel, Ioanna Maria Dimitriou, Martin Textor, Georg N. Duda, Janosch Schoon, Uwe Marx, Uwe Kornak, Annika Winter, Bernhard Hesse, Stefanie Donner, Sebastian Hardt, Oliver Klein, Simon Reinke, Malte Spielmann, Sven Geißler   +17 more
wiley   +1 more source

Endothelial Cells at the Crossroad of Atherosclerosis and Metabolic Dysfunction-Associated Steatotic Liver Disease: A Unifying Target for Dual Treatment. [PDF]

JACC Basic Transl Sci
Ben Dhaou C, Rom O, Orr AW.
europepmc   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Preclinical assessment of Preserflo MicroShunt implantation using an intraocular endoscope-holding robot. [PDF]

Sci Rep
Adachi K, Ashikaga K, Tomita K, Funaki T, Nakao S.   +4 more
europepmc   +1 more source

A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation

Advanced Science, EarlyView.
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu, Minmin Mao, Beltzane Garcia Cirera, Hao Ye, Xiangzhong Chen, Josep Puigmartí‐Luis, Ni Qin, Salvador Pané   +7 more
wiley   +1 more source

Multimodal Advanced Imaging and Long-Term Follow-Up of Peters Anomaly Type 2, With Presumed Lenticular Material in the Cornea, in a Scottish Terrier. [PDF]

Vet Ophthalmol
Sato Y, Shua-Haim T, Ledbetter EC, Hamor RE, Moore BA.   +4 more
europepmc   +1 more source

Microbial proteases and endothelial barrier disruption in sepsis: A neglected nexus. [PDF]

Virulence
Rao SS, Shenoy M S, Gutti RK, Prabhu V, Joshi M, Nayak UY, Bharath Prasad AS.   +6 more
europepmc   +1 more source

The levels of vascular endothelial cells and endothelium-dependent vasomotor cytokines in children with essential hypertension: a case-control study. [PDF]

Front Pediatr
Ma J, Cui Y, Lin Y, Liu Y, Liu Y, Shi L.
europepmc   +1 more source

Molecular Mechanisms Governing Vascular Function in Heart Failure. [PDF]

Arterioscler Thromb Vasc Biol
Garrido-Moreno V, Ferdous A, Gillette TG, Hill JA.   +3 more
europepmc   +1 more source

High-fat diet-induced obesity impairs endothelium-dependent relaxation in rabbits: association with MLCK upregulation and partial <i>ex vivo</i> improvement by ML-7. [PDF]

Front Cardiovasc Med
Li J, Zhou J, Ha Q, Gu J, Yuan H, Cheng J, Zha X, Teng J, Li L, Ding J.   +9 more
europepmc   +1 more source