Results 291 to 300 of about 605,396 (385)

Guided Bone Regeneration Membrane Materials Loaded with Chimeric Nanovesicles Promote Early Bone Defect Regeneration

Advanced Healthcare Materials, EarlyView.
Early bone regeneration is challenged by poor osteogenic microenvironments. We developed a novel guided bone regeneration (GBR) membrane: a plasma‐treated polycaprolactone (PT‐PCL) electrospun nanofiber functionalized with ultrasound sequentially extruded stromal vascular fraction chimeric vesicles (USE‐SCNVs). USE‐SCNVs require less equipment, enhance
Yufan Zhang, Yaqiong Wang, Xiaona Ning, Guichu Yue, Wenhui Zhang, Yicheng Chen, Xuelian Jia, Yu Zhang, Xiao Zhang, Zihan Lu, Simin Zhu, Fuwei Liu, Yong Zhao, Liang Kong   +13 more
wiley   +1 more source

In Vivo Antihypertensive and Ex Vivo Vasodilatory Studies of Taxifolin. [PDF]

Pharmaceuticals (Basel)
Wang X, Xu X, Tew WY, Ouyang L, Yang X, Loh HW, Xu W, Xu W, Yam MF.   +8 more
europepmc   +1 more source

Using shape effects to target antibody-coated nanoparticles to lung and brain endothelium

Proceedings of the National Academy of Sciences of the United States of America, 2013
Poornima Kolhar, A. Anselmo, Vivek Gupta, K. Pant, B. Prabhakarpandian, E. Ruoslahti, S. Mitragotri   +6 more
semanticscholar   +1 more source

Bone‐Derived dECM Hydrogels Support Tunable Microenvironments for In Vitro Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
A tunable methacrylated decellularized bone matrix hydrogel (dECM‐MA) is developed to support 3D culture of human osteoblasts. The hydrogel preserves bone‐specific ECM cues and allows precise control over mechanical properties. This system provides a customizable platform for studying osteogenic differentiation and modeling bone tissue environments for
Minne Dekker, Luke Hipwood, Akhilandeshwari Ravichandran, Dietmar W. Hutmacher, Christoph Meinert, Jacqui McGovern   +5 more
wiley   +1 more source

Effects of Cytokines (or Activating Factors) on Arterial Endothelial Cells. [PDF]

Int J Mol Sci
Dicks LMT.
europepmc   +1 more source

A Novel Core–Shell Hydrogel 3D Model for Studying Macrophage Mechanosensing and Foreign Body Giant Cell Formation

Advanced Healthcare Materials, EarlyView.
The foreign body response (FBR) to biomaterials is primarily driven by macrophages, which often fuse into destructive foreign body giant cells (FBGCs). To address the limited understanding of FBGC formation, a novel microscale core–shell hydrogel 3D model is developed using heterogeneous alginate‐collagen microcapsules with varying stiffness, offering ...
Manisha Mahanty, Wenquan Ou, Xiaoping Zhu, Jonathan S Bromberg, Xiaoming He, Shaik O. Rahaman   +5 more
wiley   +1 more source

Chemokine gradients spare graft endothelium from CD8+ T cell-mediated injury during allograft rejection. [PDF]

J Clin Invest
Krummey SM, Bromberg JS.
europepmc   +1 more source

A Novel Brain Penetrable Nanocarrier Delivers Brain‐Derived Neurotrophic Factor to Treat Alzheimer's Disease

Advanced Healthcare Materials, EarlyView.
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li, Elliya Park, Chunsheng He, Azhar Z. Abbasi, Pei Zhi, Paul E. Fraser, Andrew M. Rauth, Jeffery T. Henderson, Xiao Yu Wu   +8 more
wiley   +1 more source

Targeted volume imaging reveals early vascular interactions of Lyme disease pathogen in skin. [PDF]

Nat Commun
Strnad M, Týč J, Kitzberger F, Kopecká J, Rego ROM, Vancová M.   +5 more
europepmc   +1 more source

Tapered Pillar Design for High‐Precision Force Readout in Miniaturized Engineered Heart Tissues From Human Pluripotent Stem Cells

Advanced Healthcare Materials, EarlyView.
Engineered heart tissues (EHTs) are a valuable approach in capturing human cardiac physiology and drug responses in vitro. Here, a novel tapered pillar design is developed in an EHT platform to confine tissues in a predefined position‐ at the middle of the pillar height.
Milica Dostanić, Maury Wiendels, Laura M. Windt, Mervyn P.H. Mol, Francijna E. van den Hil, Richard P. Davis, Valeria Orlova, Berend J. van Meer, Massimo Mastrangeli, Christine L. Mummery   +9 more
wiley   +1 more source