Advances in the Development of Biomaterials for Endotoxin Adsorption in Sepsis
Frontiers in Bioengineering and Biotechnology, 2021 Sepsis, a life-threatening and intractable disease without any specific treatment, is activated by endotoxin. Some attempts at removing endotoxin to treat sepsis from the blood circulation using different hemoperfusion cartridges have been proposed ...
Qinbo Yang +12 more
doaj +1 more source
Reexamination of the Effect of Endotoxin on Cell Proliferation and Transfection Efficiency
BioTechniques, 2000 Plasmid DNA purified from bacterial cells can be contaminated with endotoxin to different extents, depending on the purification method. Earlier reports indicate that endotoxin can decrease transfection efficiency in many eukaryotic cell lines; however ...
Kimberly A. Butash +3 more
doaj +1 more source
Influence of the apical enlargement size on the endotoxin level reduction of dental root canals
Journal of Applied Oral Science, 2012 Gram-negative bacteria play an essential role in endodontic infections because they have virulence factors such as endotoxin. Due to its potential cytotoxic activity, special attention has been given to the removal/neutralization of this endotoxin in the
Ariane Cassia Salustiano Marinho +4 more
doaj +3 more sources
Mechanisms of endotoxin shock and endotoxin hypersensitivity
Immunobiology, 1993 Endotoxins (lipopolysaccharide, LPS) are biologically active substances present in Gram-negative bacteria. Injection of purified LPS into experimental animals leads to the development of many biological activities that can lead to shock with lethal outcome.
C, Galanos, M A, Freudenberg
openaire +2 more sources
Cardiovascular risk of circulating endotoxin level in prevalent hemodialysis patients
The Egyptian Heart Journal, 2018 Background: Cardiovascular diseases (CVDs) are a major cause of morbidity and mortality in patients with end stage renal disease (ESRD). Circulating endotoxins may have toxic effect on myocardial functions and are speculated as pathogens of accelerated ...
Mohamed Ibrahim +3 more
doaj +1 more source
Personal endotoxin exposure in a panel study of school children with asthma
Environmental Health, 2011 Background Endotoxin exposure has been associated with asthma exacerbations and increased asthma prevalence. However, there is little data regarding personal exposure to endotoxin in children at risk, or the relation of personal endotoxin exposure to ...
Tjoa Thomas +2 more
doaj +1 more source
Intratracheal IL-6 protects against lung inflammation in direct, but not indirect, causes of acute lung injury in mice. [PDF]
PLoS ONE, 2013 Serum and bronchoalveolar fluid IL-6 are increased in patients with acute respiratory distress syndrome (ARDS) and predict prolonged mechanical ventilation and poor outcomes, although the role of intra-alveolar IL-6 in indirect lung injury is unknown. We
Rhea Bhargava +7 more
doaj +1 more source
Lipopolysaccharide Endotoxins [PDF]
Annual Review of Biochemistry, 2002 ▪ Abstract Bacterial lipopolysaccharides (LPS) typically consist of a hydrophobic domain known as lipid A (or endotoxin), a nonrepeating “core” oligosaccharide, and a distal polysaccharide (or O-antigen). Recent genomic data have facilitated study of LPS assembly in diverse Gram-negative bacteria, many of which are human or plant pathogens, and have ...
Christian R H, Raetz, Chris, Whitfield
openaire +2 more sources
Is Endotoxemia in Stable Hemodialysis Patients an Artefact? Limitations of the Limulus Amebocyte Lysate Assay and Role of (1→3)-β-D Glucan. [PDF]
PLoS ONE, 2016 Elevated blood endotoxin levels are frequently reported in the dialysis population and are strongly linked with inflammation, a major predictor of mortality.
Jonathan Wong +5 more
doaj +1 more source