Results 21 to 30 of about 111,226 (267)
Systemic inflammatory response to inhaled endotoxin does not correlate with airway response
Background Endotoxin is a component of particulate matter linked to respiratory disease. Our group has shown that experimental endotoxin inhalation challenge reproducibly triggers neutrophilic inflammation in the airways and in peripheral blood.
Amika K. Sood +6 more
doaj +1 more source
For release of parenteral drug products, bacterial endotoxin testing is one of a panel of necessary tests. In order to ensure the validity of such tests, various controls are performed, including demonstration of compendial method suitability or method ...
René Bech Ørving +5 more
doaj +1 more source
Endotoxin Production by Pseudomonas aeruginosa ATCC 9027 with Potential Medical Applications
Four Gram-negative bacteria (E.coli ATCC 19404, P. aeruginosa ATCC9027, A. hydrophila ATCC 7966 and V. damsel ATCC 33539) were screened for production of endotoxin. P. aeruginosa recoded the highest endotoxin concentration (338.59 x 103 IU/ml).
Moustafa Y. El-Naggar +4 more
doaj +1 more source
The endotoxin of the meningococcus [PDF]
1. The view is advanced that the endotoxin of the meningococcus is one of a group of thermostable intracellular bacterial poisons, and that it is not a specific antigenic toxin. 2. The inability of the “endotoxin” to function as an antigen does not lessen its importance as a pathogenic factor in cerebrospinal fever, since the lesions that are ...
openaire +2 more sources
RationaleEndotoxin is a near ubiquitous environmental exposure that that has been associated with both asthma and chronic obstructive pulmonary disease (COPD). These obstructive lung diseases have a complex pathophysiology, making them difficult to study
Peggy S Lai +10 more
doaj +1 more source
In 1947, Paul Beeson showed that rabbits repeatedly injected with certain bacteria eventually become resistant to the bacteria's fever-provoking effects—a phenomenon known as endotoxin tolerance.
openaire +2 more sources
Seasonal Changes in Endotoxin Exposure and Its Relationship to Exhaled Nitric Oxide and Exhaled Breath Condensate pH Levels in Atopic and Healthy Children. [PDF]
Endotoxin, a component of the cell walls of gram-negative bacteria, is a contaminant in organic dusts (house dust) and aerosols. In humans, small amounts of endotoxin may cause a local inflammatory response.
Gwo-Hwa Wan +4 more
doaj +1 more source
Exposure to endotoxin, a component of gram-negative bacterial cell walls, is widespread in many industrial settings and in the ambient environment. Heavy-exposure environments include livestock farms, cotton textile facilities, and saw mills. Concentrations are highly variable in non-occupational indoor and outdoor environments.
Lundin, Jessica I., Checkoway, Harvey
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
At the present time, systemic lupus erythematosus (SLE) takes the leading place among systemic autoimmune disorders. Despite considerable progress in understanding basic pathogenesis of this disease, many subtle mechanisms of progressive inflammation in ...
D. V. Shaduro +2 more
doaj +1 more source

