Attenuation of leukocyte sequestration by selective blockade of PECAM-1 or VCAM-1 in murine endotoxemia [PDF]
Background: Molecular mechanisms regulating leukocyte sequestration into the tissue during endotoxemia and/or sepsis are still poorly understood. This in vivo study investigates the biological role of murine PECAM-1 and VCAM-1 for leukocyte sequestration
Chosay JG +25 more
core +1 more source
Intestinal epithelial responses to Salmonella enterica serovar Enteritidis: Effects on intestinal permeability and ion transport [PDF]
Salmonella infection of chickens that leads to potential human foodborne salmonellosis continues to be a major concern. Chickens serve as carriers but, in contrast to humans, rarely show any clinical signs including diarrhea.
Aschenbach, J. R. +4 more
core +1 more source
Integrated dataset on acute phase protein response in chicken challenged with Escherichia coli lipopolysaccharide endotoxin [PDF]
Data herein describe the quantitative changes in the plasma proteome in chickens challenged with lipopolysaccharide (LPS), a bacterial endotoxin known to stimulate the host innate immune system obtained by shotgun quantitative proteomic tandem mass tags ...
Bain, Maureen +7 more
core +3 more sources
Cardiovascular risk of circulating endotoxin level in prevalent hemodialysis patients
Background: Cardiovascular diseases (CVDs) are a major cause of morbidity and mortality in patients with end stage renal disease (ESRD). Circulating endotoxins may have toxic effect on myocardial functions and are speculated as pathogens of accelerated ...
Mohamed Ibrahim +3 more
doaj +1 more source
Personal endotoxin exposure in a panel study of school children with asthma
Background Endotoxin exposure has been associated with asthma exacerbations and increased asthma prevalence. However, there is little data regarding personal exposure to endotoxin in children at risk, or the relation of personal endotoxin exposure to ...
Tjoa Thomas +2 more
doaj +1 more source
Is Endotoxemia in Stable Hemodialysis Patients an Artefact? Limitations of the Limulus Amebocyte Lysate Assay and Role of (1→3)-β-D Glucan. [PDF]
Elevated blood endotoxin levels are frequently reported in the dialysis population and are strongly linked with inflammation, a major predictor of mortality.
Jonathan Wong +5 more
doaj +1 more source
In 1947, Paul Beeson showed that rabbits repeatedly injected with certain bacteria eventually become resistant to the bacteria's fever-provoking effects—a phenomenon known as endotoxin tolerance.
openaire +2 more sources
Intratracheal IL-6 protects against lung inflammation in direct, but not indirect, causes of acute lung injury in mice. [PDF]
Serum and bronchoalveolar fluid IL-6 are increased in patients with acute respiratory distress syndrome (ARDS) and predict prolonged mechanical ventilation and poor outcomes, although the role of intra-alveolar IL-6 in indirect lung injury is unknown. We
Rhea Bhargava +7 more
doaj +1 more source
Low Endotoxin Recovery—Masking of Naturally Occurring Endotoxin [PDF]
Endotoxins are cell wall components of Gram-negative bacteria. A release of endotoxins into the human blood stream results in an inflammation reaction that can lead to life-threatening conditions like sepsis. Therefore, control for endotoxin contamination of intravenously administered drugs is crucial.
Johannes Reich +4 more
openaire +3 more sources
Endotoxin Production by Pseudomonas aeruginosa ATCC 9027 with Potential Medical Applications
Four Gram-negative bacteria (E.coli ATCC 19404, P. aeruginosa ATCC9027, A. hydrophila ATCC 7966 and V. damsel ATCC 33539) were screened for production of endotoxin. P. aeruginosa recoded the highest endotoxin concentration (338.59 x 103 IU/ml).
Moustafa Y. El-Naggar +4 more
doaj +1 more source

