Results 61 to 70 of about 214,836 (286)

Endotoxin and CD14 in the progression of biliary atresia

Journal of Translational Medicine, 2010
Background Biliary atresia (BA) is a typical cholestatic neonatal disease, characterized by obliteration of intra- and/or extra-hepatic bile ducts. However, the mechanisms contributing to the pathogenesis of BA remain uncertain. Because of decreased bile
Chen Ching-Mei, Eng Hock-Liew, Chuang Jiin-Haur, Chou Ming-Huei, Wang Chiou-Huey, Chen Chao-Long, Lin Tsun-Mei   +6 more
doaj   +1 more source

An in vitro study on factors affecting endotoxin neutralization in human plasma using the Limulus amebocyte lysate test

Scientific Reports, 2021
Endotoxin neutralization, caused by plasma components, makes it difficult to detect endotoxins in human blood. In this study, we investigated which factors influence the recovery of endotoxins using limulus ameobocyte lysate (LAL)-based assays.
Stephan Harm, Claudia Schildböck, Karin Strobl, Jens Hartmann   +3 more
doaj   +1 more source

Triglyceride-rich lipoproteins prevent septic death in rats. [PDF]

, 1995
Triglyceride-rich lipoproteins bind and inactive bacterial endotoxin in vitro and prevent death when given before a lethal dose of endotoxin in animals.
Calhoun, MC, Feingold, KR, Grunfeld, C, Kane, JP, Kumwenda, ZL, Rapp, JH, Read, TE   +6 more
core  

Effects of probiotics in patients with diabetes mellitus type 2 : study protocol for a randomized, double-blind, placebo-controlled trial [PDF]

, 2013
Background: Low grade chronic inflammation is observed in patients with type 2 diabetes mellitus (T2DM). Endotoxin derived from gut bacteria may act as a potent inflammatory stimulant.
Al-Daghri, Nasser M., Al-Saleh, Yousef, Alkharfy, Khalid M., Alokail, Majed S., McTernan, P. G. (Philip G.), Sabico, Shaun, Vanhoutte, Paul M.   +6 more
core   +3 more sources

Immune and Stem Cell‐Mediated Bactericidal Amplification and Bone Remodeling for Infection Clearance and Osteointegration

Advanced Materials, EarlyView.
A pH‐responsive biomaterial interface integrates bactericidal peptides, cell‐recruiting peptides, and magnesium ions into a multifunctional system. Infection‐induced acidification triggers antimicrobial peptide release while cell‐recruiting peptides mobilize bone marrow stem cells.
Zhenyu Li, Siming Zhang, Jiale Dong, Ning Li, Mo Chen, Kunzheng Wang, Bin Li, Guoqing Pan, Jiaxiang Bai, Chen Zhu   +9 more
wiley   +1 more source

Dietary oil composition differentially modulates intestinal endotoxin transport and postprandial endotoxemia

Nutrition & Metabolism, 2013
Background Intestinal derived endotoxin and the subsequent endotoxemia can be considered major predisposing factors for diseases such as atherosclerosis, sepsis, obesity and diabetes.
Mani Venkatesh, Hollis James H, Gabler Nicholas K   +2 more
doaj   +1 more source

Roadmap to Precision 3D Printing of Cellulose: Rheology‐Guided Formulation, Fidelity Assessment, and Application Horizons

Advanced Materials Technologies, EarlyView.
This critical review presents a comprehensive roadmap for the precision 3D printing of cellulose. Quantitative correlations link ink formulation and rheological properties to print fidelity and final material performance. This framework guides the development of advanced functional materials, from biomedical scaffolds to electromagnetic shielding ...
Majed Amini, Hadi Hosseini, Seyyed Alireza Hashemi, Mohammad Arjmand   +3 more
wiley   +1 more source

A non-linear mixed effect model for innate immune response: In vivo kinetics of endotoxin and its induction of the cytokines tumor necrosis factor alpha and interleukin-6.

PLoS ONE, 2019
Endotoxin, a component of the outer membrane of Gram-negative bacteria, has been extensively studied as a stimulator of the innate immune response. However, the temporal aspects and exposure-response relationship of endotoxin and resulting cytokine ...
Anders Thorsted, Salim Bouchene, Eva Tano, Markus Castegren, Miklós Lipcsey, Jan Sjölin, Mats O Karlsson, Lena E Friberg, Elisabet I Nielsen   +8 more
doaj   +1 more source

L-selectin and beta(2)-integrin expression on circulating bovine polymorphonuclear leukocytes during endotoxin mastitis [PDF]

, 2003
The aim of this in vivo study was to examine the effect of intramammarily administered endotoxin (lipopolysaccharide, LPS) on the expression of L-selectin (CD62L) and the beta(2)-integrin subunits CD11b and CD18 on circulating bovine PMN.
Burvenich, Christian, Diez Fraile, Araceli, Duchateau, Luc, Meyer, Evelyne   +3 more
core  

Predicting Macrophage Spatial Localization from Single‐Cell Transcriptomes to Uncover Disease Mechanisms

Advanced Science, EarlyView.
This study presents a machine‐learning framework entitled MERLIN that infers the microanatomical localization of macrophages from single‐cell transcriptomic data in structured organs such as the kidney and brain. Applying this method to existing datasets from models of acute kidney injury and diabetic nephropathy uncovered spatially resolved insights ...
Junping Yin, Qi Mei, Hans‐Joachim Paust, Ning Song, Yu Zhao, Daniela Klaus, Melanie Eichler, Yijun Hua, Jie Qin, Weiting Cheng, Christina K. Weisheit, Veronika Lukacs‐Kornek, Isis Ludwig‐Portugall, Sibylle von Vietinghoff, Christian F. Krebs, Johanna Klughammer, Ulf Panzer, Christian Kurts, Jian Li   +18 more
wiley   +1 more source